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Which class of antiretroviral drugs targets the stage of the HIV lifecycle by inhibiting RNA from forming DNA?

A.

Fusion Inhibitors

B.

Integrase Inhibitors

C.

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

D.

Protease Inhibitors

Answer and Explanation

The Correct Answer is C

A. Fusion Inhibitors work by preventing the virus from entering the host's cells but do not inhibit RNA from forming DNA.  

 

B. Integrase Inhibitors block the integration of viral DNA into the host's DNA but do not directly inhibit the reverse transcription process.  

 

C. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) inhibit reverse transcriptase, the enzyme responsible for converting viral RNA into DNA, thus directly targeting this crucial stage of the HIV lifecycle.  

 

D. Protease Inhibitors inhibit the protease enzyme involved in the maturation of the virus but do not affect the reverse transcription process.


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Correct Answer is A

Explanation

A. A phlebotomist collecting blood from clients who have HIV is at the greatest risk due to the potential for exposure to infected blood, especially if safety precautions are not properly followed.

B. A nurse working for an insurance company collecting urine samples is at a lower risk, as urine is not a primary mode of HIV transmission.

C. A personal trainer working with a client who has HIV may be at risk if there are open wounds, but the risk is less compared to healthcare workers directly handling blood.

D. An occupational therapist working with a client who has HIV may have some exposure risk, but it is significantly lower than that of a phlebotomist who handles blood samples.

Correct Answer is C

Explanation

A. Fusion Inhibitors work by preventing the virus from entering the host's cells but do not inhibit RNA from forming DNA.

B. Integrase Inhibitors block the integration of viral DNA into the host's DNA but do not directly inhibit the reverse transcription process.

C. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) inhibit reverse transcriptase, the enzyme responsible for converting viral RNA into DNA, thus directly targeting this crucial stage of the HIV lifecycle.

D. Protease Inhibitors inhibit the protease enzyme involved in the maturation of the virus but do not affect the reverse transcription process.

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