Which class of antiretroviral drugs targets the stage of the HIV lifecycle by inhibiting RNA from forming DNA?
Fusion Inhibitors
Integrase Inhibitors
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Protease Inhibitors
The Correct Answer is C
A. Fusion Inhibitors work by preventing the virus from entering the host's cells but do not inhibit RNA from forming DNA.
B. Integrase Inhibitors block the integration of viral DNA into the host's DNA but do not directly inhibit the reverse transcription process.
C. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) inhibit reverse transcriptase, the enzyme responsible for converting viral RNA into DNA, thus directly targeting this crucial stage of the HIV lifecycle.
D. Protease Inhibitors inhibit the protease enzyme involved in the maturation of the virus but do not affect the reverse transcription process.
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View Related questions
Correct Answer is B
Explanation
A. Increased systemic vascular resistance is typically associated with hypovolemic or cardiogenic shock, not distributive shock.
B. Distributive shock is characterized by systemic vasodilation, which leads to a decrease in systemic vascular resistance and results in inadequate tissue perfusion despite normal or increased cardiac output.
C. Loss of myocardial contractility is related to cardiogenic shock, not distributive shock.
D. Loss of blood volume is a characteristic of hypovolemic shock, whereas distributive shock occurs even when blood volume is normal due to vasodilation.
Correct Answer is A
Explanation
A. Binding is the initial step where the HIV virus attaches to the CD4 receptor on the host cell's surface. This interaction is crucial for the subsequent entry of the virus into the host cell.
B. Integration occurs later in the lifecycle, after the virus has entered the host cell and its RNA is converted to DNA.
C. Fusion refers to the process where the viral envelope fuses with the host cell membrane to allow entry into the cell, which follows the binding stage.
D. Reverse Transcription is the process of converting viral RNA into DNA after the virus has entered the host cell, and is not involved in the attachment phase.