When caring for a patient who has been admitted for his heart failure, the nurse observes that the patient is experiencing bradycardia. Which drug should be administered to patients who develop bradycardia?
Atropine
Cholestyramine
Inamrinone
Milrinone
The Correct Answer is A
A. Atropine is an anticholinergic medication that increases heart rate by blocking vagal effects on the heart, making it the first-line treatment for symptomatic bradycardia.
B. Cholestyramine is a bile acid sequestrant used to lower cholesterol levels and does not have any effects on heart rate.
C. Inamrinone is a phosphodiesterase inhibitor used in heart failure for inotropic support but is not specifically indicated for bradycardia management.
D. Milrinone is also a phosphodiesterase inhibitor used for heart failure but does not address bradycardia directly.
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Correct Answer is B
Explanation
A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.
B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.
C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.
D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.
Correct Answer is B
Explanation
A. While resting heart rate and blood pressure are important for overall cardiovascular health, they do not specifically assess the effectiveness of atorvastatin in lowering lipid levels.
B. Reviewing laboratory blood work results, particularly lipid panels, is essential to determine the therapeutic effect of atorvastatin, as it directly measures changes in cholesterol levels (such as LDL and total cholesterol).
C. Assessing exercise tolerance and activities of daily living can provide insight into overall health and well-being but does not specifically evaluate the impact of atorvastatin on lipid levels.
D. A focused cardiac assessment is beneficial for understanding cardiovascular health but is not specific for measuring the effectiveness of lipid-lowering therapy with atorvastatin.