What measure protects the nurse when preparing cytotoxic drugs?
Wearing protective equipment such as gloves, mask, and gown
Washing hands before preparation
Mixing medication in a 1-L bag
Administering medication IM
The Correct Answer is A
A. Wearing protective equipment such as gloves, mask, and gown is essential when preparing cytotoxic drugs to protect the nurse from potential exposure to harmful substances.
B. While washing hands is important for general hygiene, it does not specifically protect against cytotoxic drug exposure.
C. Mixing medication in a 1-L bag does not offer specific protection to the nurse and is not a standard measure for safety.
D. Administering medication intramuscularly (IM) is a route of administration and does not relate to protection measures while preparing cytotoxic drugs.
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Correct Answer is D
Explanation
A. By directly relaxing vascular smooth muscle is not how lisinopril primarily works; it does not act directly on smooth muscle but rather affects hormonal pathways.
B. By blocking aldosterone from binding to mineralocorticoid receptors is a secondary effect of the angiotensin-converting enzyme (ACE) inhibitors but not the primary action of lisinopril itself.
C. By blocking the movement of calcium ions into arterial smooth muscles describes the action of calcium channel blockers, not ACE inhibitors like lisinopril.
D. By inhibiting the transformation of angiotensin I to angiotensin II is the correct answer because lisinopril inhibits the ACE enzyme, reducing the production of angiotensin II, which lowers blood pressure and decreases strain on the heart.
Correct Answer is A
Explanation
A. An INR of 5.0 indicates a significantly increased risk of bleeding, and administering vitamin K is the appropriate antidote for reversing the effects of warfarin. This is a critical intervention to restore coagulation.
B. Increasing the dose of warfarin is inappropriate in this scenario because the INR is already elevated; it would further increase bleeding risk.
C. While heparin can be used for anticoagulation, it is not appropriate to administer it while the INR is dangerously high without reversing the warfarin first.
D. Continuing warfarin is unsafe at this INR level due to the high risk of bleeding; monitoring for symptoms without intervention is not adequate care.