What is the significance of elevated serum levels of troponin?
This intracellular substance can leak into the blood with cardiac cellular injury or death.
Elevated serum levels of troponin occur because of sustained glycogenolysis.
This substance is elevated when a patient has acute tubular necrosis.
Serum elevation of this acute phase reactant occurs because of tissue injury.
The Correct Answer is A
Choice A rationale
Elevated serum levels of troponin indicate cardiac cellular injury or death. Troponin is a protein released into the bloodstream when heart muscle cells are damaged, such as during a myocardial infarction.
Choice B rationale
Sustained glycogenolysis does not cause elevated troponin levels. Glycogenolysis is the breakdown of glycogen to glucose, primarily occurring in the liver and muscles, not related to troponin release.
Choice C rationale
Acute tubular necrosis does not elevate troponin levels. This condition affects the renal tubules and is typically indicated by elevated creatinine and BUN levels.
Choice D rationale
Troponin is not an acute phase reactant. Acute phase reactants are proteins whose levels change in response to inflammation, such as C-reactive protein (CRP), not troponin.
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Correct Answer is D
Explanation
Choice A rationale
Poor blood glucose control is a significant factor in delayed wound healing in patients with diabetes. Hyperglycemia impairs various aspects of the immune response, reduces blood flow, and increases the risk of infection, all of which contribute to delayed healing.
Choice B rationale
Inadequate protein intake can also contribute to delayed wound healing. Protein is essential for the repair and regeneration of tissues, and a deficiency can impair the body’s ability to heal wounds effectively.
Choice C rationale
Peripheral neuropathy, a common complication of diabetes, can lead to decreased sensation in the feet, making it more likely for injuries to go unnoticed and untreated. This can result in chronic wounds and delayed healing.
Choice D rationale
All of the above factors—poor blood glucose control, inadequate protein intake, and peripheral neuropathy—can contribute to delayed healing of foot ulcers in patients with diabetes. Each of these factors plays a role in the complex process of wound healing and can hinder the body’s ability to repair itself.
Correct Answer is D
Explanation
ChoiceArationale
Post-renalacute kidneyinjury(AKI)iscausedbyobstructionofurineflow,leadingto decreased urine output, but it does not typically cause crackles in the lungs.
ChoiceBrationale
Diabetesinsipidus(DI)ischaracterizedbyexcessiveurinationandthirstduetoadeficiencyof antidiuretic hormone (ADH), but it does not cause crackles in the lungs.
ChoiceCrationale
Syndromeofinappropriateantidiuretichormone(SIADH)involvesexcessivereleaseofADH, leading to water retention and hyponatremia, but it does not cause crackles in the lungs.
ChoiceDrationale
Congestiveheartfailure(CHF)canleadtofluidaccumulationinthelungs(crackles)and decreased urine output due to poor cardiac function and renal perfusion.