What is the major reason that monoamine oxidase inhibitors (MAOIs) are rarely used in clinical practice today?
They are under a scheduled drug classification.
They are ineffective in treating depression or anxiety disorders.
They can cause gastrointestinal (GI) bleeding and esophageal varices.
They may cause dangerous interactions with some foods and drugs.
The Correct Answer is D
A. While MAOIs may have some regulatory considerations, they are not classified under a scheduled drug classification like controlled substances.
B. MAOIs are effective in treating depression and anxiety disorders, which is not the reason for their limited use.
C. Although MAOIs can have some side effects, they are more notably associated with dietary and drug interactions rather than causing GI bleeding or esophageal varices.
D. MAOIs can cause dangerous interactions with foods that contain tyramine (like aged cheeses and fermented products) and certain medications, leading to hypertensive crises, making their use cautious and limiting in clinical practice.
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Correct Answer is C
Explanation
A. Chest pain and pale skin are not typical adverse effects associated with diltiazem use.
B. Shortness of breath and wheezing may occur due to other conditions or medications but are not common adverse effects of diltiazem.
C. Calcium channel blockers like diltiazem can cause peripheral edema due to vasodilation and bradycardia as a result of their action on the heart rate. Monitoring for these effects is essential in patients taking diltiazem.
D. Tachycardia is not an expected adverse effect of diltiazem; in fact, it is used to manage conditions where tachycardia may be present. Anxiety is also not a direct adverse effect of this medication.
Correct Answer is ["B","C","D"]
Explanation
A. Sitting up comfortably in bed is not ideal for nasal spray administration; the client should be in an upright position, possibly sitting on the edge of a chair.
B. Tilting the head slightly to the side is correct; this position helps the medication to be delivered effectively to the nasal passages.
C. Inserting the tip of the nose piece into one nostril is correct; this ensures that the medication is delivered directly into the nasal cavity.
D. Holding the breath for a few seconds after administering the spray is correct; this allows for better absorption of the medication in the nasal mucosa.
E. Blowing the nose 1 minute after administering the spray is incorrect; the client should avoid blowing their nose for at least a few minutes after administration to allow the medication to be absorbed effectively.