What adverse reaction does the nurse anticipate if a client takes nitroglycerin with sildenafil?
Hypotension
Bradycardia
Chest pain
Nausea
The Correct Answer is A
A. The combination of nitroglycerin and sildenafil can lead to severe hypotension due to the vasodilatory effects of both medications. This is the most critical adverse reaction the nurse should anticipate.
B. Bradycardia is not a direct effect of this combination; rather, hypotension is a more significant concern.
C. Chest pain may occur if hypotension leads to inadequate perfusion, but it is not a direct adverse effect of the drug interaction.
D. Nausea can occur with various medications, but it is not specifically linked to the interaction between nitroglycerin and sildenafil.
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Correct Answer is D
Explanation
A. While MAOIs may have some regulatory considerations, they are not classified under a scheduled drug classification like controlled substances.
B. MAOIs are effective in treating depression and anxiety disorders, which is not the reason for their limited use.
C. Although MAOIs can have some side effects, they are more notably associated with dietary and drug interactions rather than causing GI bleeding or esophageal varices.
D. MAOIs can cause dangerous interactions with foods that contain tyramine (like aged cheeses and fermented products) and certain medications, leading to hypertensive crises, making their use cautious and limiting in clinical practice.
Correct Answer is A
Explanation
A. Spironolactone is a potassium-sparing diuretic, meaning it helps retain potassium while promoting sodium and water excretion. This makes it advantageous for clients who may be at risk for hypokalemia with furosemide, which can lead to significant potassium loss.
B. This statement is incorrect; spironolactone causes less potassium loss compared to furosemide, making it a better option for those needing to maintain potassium levels.
C. This statement is misleading; spironolactone does promote diuresis but does not cause greater water losses than furosemide.
D. This is incorrect; while spironolactone does promote sodium excretion, it does not do so to a greater extent than furosemide, which is a more potent diuretic.