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The nurse knows the rationale for combination chemotherapy is to:

A.

limit episodes of anticipatory and delayed emesis

B.

lessen the client's risk of developing neutropenia

C.

decrease time intervals between remission

D.

broaden range of cell kill while minimizing toxicities to the client

Answer and Explanation

The Correct Answer is D

A. While limiting emesis is important in cancer treatment, combination chemotherapy primarily focuses on improving efficacy and minimizing toxicities, not specifically targeting nausea and vomiting episodes.  

 

B. Combination chemotherapy can actually increase the risk of neutropenia due to the cumulative effects of multiple agents, as each may independently lower white blood cell counts.  

 

C. Decreasing time intervals between remission is not a primary goal of combination chemotherapy; rather, it aims to achieve better overall treatment outcomes.  

 

D. The main rationale for using combination chemotherapy is to broaden the range of cancer cell kill through different mechanisms of action while minimizing the side effects associated with higher doses of a single agent. This approach can improve treatment efficacy and reduce the likelihood of resistance. 


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View Related questions

Correct Answer is C

Explanation

A. Using a soft toothbrush is appropriate for preventing bleeding, but it does not directly indicate an understanding of neutropenia or its implications for infection risk.

B. Babysitting a young child may expose the client to infections, which is not safe for someone with neutropenia. This statement shows a lack of understanding.

C. Calling the oncologist when experiencing an increased temperature is critical because it may indicate an infection, which is a major concern for clients with neutropenia. This statement reflects an appropriate understanding of the condition.

D. While wearing a mask can be beneficial in some situations, stating that it must be worn at all times is not necessary and shows a misunderstanding of the guidelines for reducing infection risk in neutropenia.

Correct Answer is C

Explanation

A. Large tumors with distant metastasis may not respond well to radiation therapy, as the effectiveness diminishes when cancer spreads beyond the primary site.

B. While radiation can be effective for superficial cancers, it is most impactful when the cancer is localized.

C. Radiation therapy is most effective for localized cancers, where the treatment can target the tumor directly without affecting surrounding healthy tissues extensively.

D. Cancer spread to multiple sites in one organ complicates treatment and may reduce the efficacy of radiation therapy, as multiple targets may require different approaches.

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