The nurse is caring for an immunosuppressed pediatric client who reports soreness in his mouth and refuses to eat. Inspection of his mouth reveals a white, milky plaque that does not come off with rubbing. The nurse should anticipate which drug to be administered to this client?
nystatin (Mycostatin)
amoxicillin (Amoxil)
metronidazole (Flagyl)
acyclovir (Zovirax)
The Correct Answer is A
A. Nystatin is an antifungal medication used to treat oral candidiasis (thrush), which is consistent with the client's symptoms of soreness in the mouth and the presence of a white, milky plaque that does not rub off.
B. Amoxicillin is an antibiotic that treats bacterial infections but would not be effective against fungal infections like oral thrush.
C. Metronidazole is an antibiotic and antiprotozoal medication, which is not appropriate for treating oral candidiasis.
D. Acyclovir is an antiviral medication used to treat infections caused by certain viruses, such as herpes, and is not effective for fungal infections like thrush.
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Correct Answer is C
Explanation
A. Grapefruit juice does not have a known interaction with metronidazole and does not need to be avoided.
B. Dairy does not interfere with metronidazole's absorption or effectiveness, so it is not a contraindication.
C. Alcohol should be strictly avoided during and for at least 48 hours after metronidazole treatment, as it can cause a severe reaction, including nausea, vomiting, flushing, and rapid heart rate.
D. Tyramine-based foods do not interact with metronidazole, so they are not a contraindication for this medication.
Correct Answer is C
Explanation
A. Risperidone is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder, not first-line treatment for depression.
B. Haloperidol is a typical antipsychotic used mainly for acute psychosis and agitation, not for treating depression.
C. Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that is widely recognized as a first-line treatment for depression due to its efficacy and relatively favorable side effect profile.
D. Clozapine is an atypical antipsychotic reserved for treatment-resistant schizophrenia and is not indicated for the treatment of depression.