The nurse is caring for a client who experienced a dry-non productive cough associated with an ACE inhibitor. Which of the following drugs is an alternative to ACE inhibitors?
losartan (Cozaar)
metoprolol (Lopressor)
furosemide (Lasix)
hydralazine HCL (Apresoline)
The Correct Answer is A
A. Losartan is an angiotensin receptor blocker (ARB) that serves as an effective alternative to ACE inhibitors, particularly for patients who experience cough as a side effect.
B. Metoprolol is a beta-blocker, which is not a direct alternative to ACE inhibitors and is used for different indications such as heart rate and blood pressure control.
C. Furosemide is a diuretic that does not directly substitute for the actions of ACE inhibitors.
D. Hydralazine is a direct vasodilator used for hypertension but does not share the same mechanism as ACE inhibitors or serve as a direct alternative.
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Correct Answer is A
Explanation
A. Losartan is an angiotensin receptor blocker (ARB) that serves as an effective alternative to ACE inhibitors, particularly for patients who experience cough as a side effect.
B. Metoprolol is a beta-blocker, which is not a direct alternative to ACE inhibitors and is used for different indications such as heart rate and blood pressure control.
C. Furosemide is a diuretic that does not directly substitute for the actions of ACE inhibitors.
D. Hydralazine is a direct vasodilator used for hypertension but does not share the same mechanism as ACE inhibitors or serve as a direct alternative.
Correct Answer is D
Explanation
A. Increased creatinine clearance is not a common effect of gemfibrozil; rather, it may lead to liver function changes or muscle-related side effects.
B. Gemfibrozil does not typically decrease prothrombin time (PT); this option does not relate to its mechanism of action.
C. Hyperkalemia is not a typical side effect of gemfibrozil; it may be more relevant to other medications, particularly those affecting the kidneys.
D. Gallstones are a known side effect of gemfibrozil, as the drug can increase biliary cholesterol saturation, leading to the formation of stones.