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The nurse is caring for a client receiving ciprofloxacin for treatment of a urinary tract infection (UTI). The nurse will include which black box warning (BBW) in the discharge education?

A.

This medication can cause thromboembolic events

B.

This drug has a black box warning for causing tendon rupture

C.

This medication can cause endometrial cancers

D.

This medication can cause breast cancer

Answer and Explanation

The Correct Answer is B

A. Thromboembolic events: This is not a black box warning for ciprofloxacin.

 

B. This drug has a black box warning for causing tendon rupture: Ciprofloxacin, a fluoroquinolone, has a black box warning for the risk of tendonitis and tendon rupture, especially in older adults or those on corticosteroids.

 

C. Endometrial cancers: Ciprofloxacin is not associated with cancer.

 

D. Breast cancer: There is no link between ciprofloxacin and breast cancer.


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Correct Answer is B

Explanation

A. Staining of teeth: Rifampin is not known to stain teeth.

B. Orange colored secretions: Rifampin commonly causes orange discoloration of body fluids, including urine, tears, and sweat. This is harmless but can be alarming if the client is not forewarned.

C. Constipation: Constipation is not a typical side effect of rifampin.

D. White-colored stools: Rifampin does not cause white-colored stools, but bile duct obstruction could.

Correct Answer is D

Explanation

A. Macrolides: Macrolides, such as azithromycin or erythromycin, are often used as alternatives in clients with a penicillin allergy, as they do not have a beta-lactam ring and generally do not cause cross-reactivity.

B. Antiretrovirals: Antiretrovirals are used for treating HIV/AIDS and are unrelated to penicillin antibiotics, with no cross-sensitivity concerns.

C. Antimalarials: Antimalarial drugs are used to treat malaria and are not related to penicillin antibiotics, so they would not be a concern for cross-sensitivity.

D. Cephalosporins: Cephalosporins have a beta-lactam structure similar to penicillins, which can sometimes cause cross-reactivity in clients with a penicillin allergy. However, the risk is lower with newer generations.

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