The nurse is administering an estrogen blocker to a client diagnosed with advanced breast cancer. Which of the following side effects will the nurse caution the client regarding?
Tendon rupture
Phlebitis
Increase risk of lymphomas
Thromboembolic events
The Correct Answer is D
A. Tendon rupture: Tendon rupture is not a side effect associated with estrogen blockers.
B. Phlebitis: While thromboembolic events are a risk, phlebitis (inflammation of a vein) is not a typical concern.
C. Increased risk of lymphomas: Estrogen blockers are not known to increase the risk of lymphomas.
D. Thromboembolic events: Estrogen blockers, such as tamoxifen, are associated with an increased risk of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism).
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Correct Answer is D
Explanation
A. Macrolides: Macrolides, such as azithromycin or erythromycin, are often used as alternatives in clients with a penicillin allergy, as they do not have a beta-lactam ring and generally do not cause cross-reactivity.
B. Antiretrovirals: Antiretrovirals are used for treating HIV/AIDS and are unrelated to penicillin antibiotics, with no cross-sensitivity concerns.
C. Antimalarials: Antimalarial drugs are used to treat malaria and are not related to penicillin antibiotics, so they would not be a concern for cross-sensitivity.
D. Cephalosporins: Cephalosporins have a beta-lactam structure similar to penicillins, which can sometimes cause cross-reactivity in clients with a penicillin allergy. However, the risk is lower with newer generations.
Correct Answer is B
Explanation
A. Thromboembolic events: This is not a black box warning for ciprofloxacin.
B. This drug has a black box warning for causing tendon rupture: Ciprofloxacin, a fluoroquinolone, has a black box warning for the risk of tendonitis and tendon rupture, especially in older adults or those on corticosteroids.
C. Endometrial cancers: Ciprofloxacin is not associated with cancer.
D. Breast cancer: There is no link between ciprofloxacin and breast cancer.