Drugs can produce a wide variety of effects in addition to the desired pharmacological effect. Sometimes the drug dose can be adjusted so that the desired effect is achieved without producing undesired secondary reactions. Which are examples of this secondary action?
Spontaneous bleeding after taking an anticoagulant
Dizziness after starting an antihypertensive
Drowsiness after taking an antihistamine
Diarrhea after taking an antibiotic
Correct Answer : A,B,C,D
A. Spontaneous bleeding after taking an anticoagulant is a secondary action that occurs due to the anticoagulant's effect on blood clotting, which is an undesired effect when it leads to excessive bleeding.
B. Dizziness after starting an antihypertensive is a common secondary action related to the lowering of blood pressure, which can lead to hypotension and resultant dizziness.
C. Drowsiness after taking an antihistamine is a well-known secondary action, especially with first-generation antihistamines, which can cause sedation as a side effect.
D. Diarrhea after taking an antibiotic is a secondary action that can occur due to disruption of the normal gut flora, leading to gastrointestinal upset. All these examples illustrate secondary effects of medications.
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Correct Answer is D
Explanation
A. Liver failure does not have a direct contraindication with bronchodilators, though careful monitoring is needed.
B. Renal failure is not a direct contraindication for bronchodilator use; however, kidney function can affect drug metabolism and clearance.
C. Respiratory failure may necessitate bronchodilator therapy rather than caution, especially in conditions like COPD or asthma where bronchodilators are crucial for management.
D. Heart failure requires caution with bronchodilators because they can lead to increased heart rate and blood pressure, potentially exacerbating heart failure symptoms or leading to arrhythmias.
Correct Answer is C
Explanation
A. Sublingual administration involves placing the tablet under the tongue, not between the cheek and gums.
B. Transdermal refers to medication delivered through the skin via a patch, which is not applicable in this scenario.
C. Buccal administration involves placing the medication between the cheek and gums, allowing it to dissolve and be absorbed through the oral mucosa.
D. Translingual refers to administering a medication via the tongue, which is not the route being used in this case.