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A patient with long-term asthma develops Cushing syndrome. What is the cause of this condition?

A.

Abruptly withdrawing cortisone therapy

B.

Poorly functioning adrenal glands

C.

Lacking ACTH, related to the pituitary gland

D.

Taking corticosteroids for many years

Answer and Explanation

The Correct Answer is D

Rationale:


A. Abruptly withdrawing corticosteroid therapy can lead to adrenal insufficiency, not Cushing syndrome.


B. Poorly functioning adrenal glands cause Addison’s disease, not Cushing syndrome.


C. Lacking ACTH leads to secondary adrenal insufficiency, not Cushing syndrome.


D. Taking corticosteroids for many years can result in exogenous Cushing syndrome due to prolonged exposure to high cortisol levels, which mimic the effects of endogenous Cushing syndrome.


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View Related questions

Correct Answer is C

Explanation

Rationale:

A. In hyperparathyroidism, calcium levels are typically increased due to excessive parathyroid hormone activity, leading to calcium mobilization from bones.

B. Parathyroid hormone levels would generally be increased in hyperparathyroidism as the parathyroid glands produce more hormone in response to low calcium levels, but the condition itself is defined by elevated hormone levels.

C. Increased phosphate levels are expected due to the effects of elevated parathyroid hormone causing increased renal excretion of phosphate while allowing calcium to rise.

D. Magnesium levels can vary, but they are not typically significantly elevated in hyperparathyroidism; thus, increased magnesium is not a standard finding.

Correct Answer is B

Explanation

Rationale:

A. A 2-hour blood glucose of 132 mg/dL is within normal limits, as levels under 140 mg/dL are considered normal after an oral glucose tolerance test.

B. A fasting blood glucose level of 155 mg/dL is above the normal threshold (greater than 126 mg/dL indicates diabetes).

C. A casual blood glucose of 178 mg/dL suggests hyperglycemia but does not meet the diagnostic criteria for diabetes unless associated with symptoms.

D. An HbA1c of 5.2% is well within the normal range (below 5.7%).

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