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A patient with long-term asthma develops Cushing syndrome. What is the cause of this condition?

A.

Abruptly withdrawing cortisone therapy

B.

Poorly functioning adrenal glands

C.

Lacking ACTH, related to the pituitary gland

D.

Taking corticosteroids for many years

Answer and Explanation

The Correct Answer is D

Rationale:


A. Abruptly withdrawing corticosteroid therapy can lead to adrenal insufficiency, not Cushing syndrome.


B. Poorly functioning adrenal glands cause Addison’s disease, not Cushing syndrome.


C. Lacking ACTH leads to secondary adrenal insufficiency, not Cushing syndrome.


D. Taking corticosteroids for many years can result in exogenous Cushing syndrome due to prolonged exposure to high cortisol levels, which mimic the effects of endogenous Cushing syndrome.


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View Related questions

Correct Answer is C

Explanation

Rationale:

A. A butterfly rash is associated with systemic lupus erythematosus (SLE), not Cushing's syndrome.

B. Muscle hypertrophy is not typically seen in Cushing's syndrome; instead, muscle wasting may occur due to excess cortisol.

C. Moon face is a classic sign of Cushing's syndrome, resulting from fat redistribution caused by elevated cortisol levels.

D. A positive Chvostek's sign indicates hypocalcemia, which is not a finding associated with Cushing's syndrome.

Correct Answer is A

Explanation

Rationale:

A. Weight gain is common in hypothyroidism due to a slowed metabolism.

B. Diaphoresis is more associated with hyperthyroidism, not hypothyroidism.

C. Palpitations are a symptom of hyperthyroidism.

D. Protruding eyeballs (exophthalmos) is associated with Graves' disease, a form of hyperthyroidism.

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