A patient receiving metoclopramide is also taking an antidepressant. What should the nurse monitor for?
Decreased appetite
Increased risk of serotonin syndrome
Elevated blood pressure
Enhanced antidepressant effects
The Correct Answer is B
A. Decreased appetite may occur but is not the most critical concern in this context.
B. The combination of metoclopramide, which can influence serotonin pathways, with certain antidepressants, especially SSRIs, increases the risk of serotonin syndrome, a potentially life-threatening condition.
C. While some antidepressants can influence blood pressure, monitoring for elevated blood pressure is not the primary concern with metoclopramide.
D. There is no evidence to suggest that metoclopramide enhances the effects of antidepressants; the focus should be on potential adverse interactions instead.
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Correct Answer is C
Explanation
A. An increased risk for CNS depression is not typically associated with opioid agonist-antagonists; instead, these medications may produce a ceiling effect on sedation compared to full agonists.
B. Respiratory depression is more commonly associated with full opioid agonists rather than agonist-antagonists. Agonist-antagonists can sometimes counteract respiratory depression caused by full agonists.
C. Opioid withdrawal symptoms can occur when a client who is dependent on full agonist opioids is given an agonist-antagonist, as these medications can displace the agonist from receptors, leading to withdrawal.
D. Hypotension is a possible side effect of opioids but is not a specific concern with the use of agonist-antagonists in the context of opioid therapy.
Correct Answer is C
Explanation
A. Sublingual administration involves placing the tablet under the tongue, not between the cheek and gums.
B. Transdermal refers to medication delivered through the skin via a patch, which is not applicable in this scenario.
C. Buccal administration involves placing the medication between the cheek and gums, allowing it to dissolve and be absorbed through the oral mucosa.
D. Translingual refers to administering a medication via the tongue, which is not the route being used in this case.