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A patient is prescribed metoclopramide for the treatment of gastroparesis. Which of the following is a primary effect of metoclopramide?

A.

Reduces gastric acid secretion

B.

Enhances gastrointestinal motility

C.

Relieves abdominal pain

D.

Acts as an antiemetic by inhibiting serotonin

Answer and Explanation

The Correct Answer is B

A. While metoclopramide may have some effect on gastric acid secretion, its primary role is not to reduce it.  

 

B. Metoclopramide primarily enhances gastrointestinal motility, which helps to facilitate gastric emptying and is especially useful in treating conditions like gastroparesis.  

 

C. Metoclopramide does not specifically relieve abdominal pain; it focuses more on motility and nausea.  

 

D. Although metoclopramide does have antiemetic properties, it primarily acts as a dopamine receptor antagonist rather than directly inhibiting serotonin.


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View Related questions

Correct Answer is B

Explanation

A. While resting heart rate and blood pressure are important for overall cardiovascular health, they do not specifically assess the effectiveness of atorvastatin in lowering lipid levels.

B. Reviewing laboratory blood work results, particularly lipid panels, is essential to determine the therapeutic effect of atorvastatin, as it directly measures changes in cholesterol levels (such as LDL and total cholesterol).

C. Assessing exercise tolerance and activities of daily living can provide insight into overall health and well-being but does not specifically evaluate the impact of atorvastatin on lipid levels.

D. A focused cardiac assessment is beneficial for understanding cardiovascular health but is not specific for measuring the effectiveness of lipid-lowering therapy with atorvastatin.

Correct Answer is B

Explanation

A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.

B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.

C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.

D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.

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