A patient is prescribed metoclopramide for the treatment of gastroparesis. Which of the following is a primary effect of metoclopramide?
Reduces gastric acid secretion
Enhances gastrointestinal motility
Relieves abdominal pain
Acts as an antiemetic by inhibiting serotonin
The Correct Answer is B
A. While metoclopramide may have some effect on gastric acid secretion, its primary role is not to reduce it.
B. Metoclopramide primarily enhances gastrointestinal motility, which helps to facilitate gastric emptying and is especially useful in treating conditions like gastroparesis.
C. Metoclopramide does not specifically relieve abdominal pain; it focuses more on motility and nausea.
D. Although metoclopramide does have antiemetic properties, it primarily acts as a dopamine receptor antagonist rather than directly inhibiting serotonin.
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Correct Answer is B
Explanation
A. Prothrombin time (PT) is used to monitor warfarin therapy, not heparin therapy.
B. Activated partial thromboplastin time (aPTT) is the primary laboratory test used to assess the effectiveness of heparin therapy, measuring the time it takes for blood to clot and ensuring therapeutic levels.
C. The International normalized ratio (INR) is also related to warfarin therapy rather than heparin.
D. Serum potassium level is not relevant for assessing heparin therapy but may be monitored for other reasons.
Correct Answer is A
Explanation
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C. Clients requiring dialysis have impaired renal function, affecting drug excretion more than metabolism, so they may not necessarily have impaired drug metabolism.
D. Dehydration following diarrhea can affect the body's overall function, but it is less directly related to impaired drug metabolism compared to liver dysfunction.