A patient has been prescribed oral tetracycline for the treatment of acne. Which of the following must the nurse include in the patient teaching plan?
Take the drug on an empty stomach.
Take the drug along with a meal.
Take the drug along with milk or fruit juice.
Take the drug immediately after meals.
The Correct Answer is A
A. Take the drug on an empty stomach is correct because tetracycline should be taken without food for optimal absorption, ideally 1 hour before or 2 hours after meals.
B. Take the drug along with a meal is incorrect as it can reduce the absorption of tetracycline.
C. Take the drug along with milk or fruit juice is incorrect because calcium and magnesium can bind to tetracycline, decreasing its effectiveness.
D. Take the drug immediately after meals is also incorrect as food can hinder absorption, making this timing ineffective for treatment.
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Correct Answer is C
Explanation
A. Hypertension can affect drug distribution to some extent due to altered perfusion but is not the most significant factor impacting distribution, especially for a local condition like cellulitis.
B. Liver dysfunction primarily affects the metabolism and clearance of drugs rather than their distribution, although it may indirectly influence distribution by altering protein binding.
C. Peripheral vascular disease significantly impacts blood flow to the extremities, which can hinder the distribution of the antibiotic to the affected area (the left leg) where the cellulitis is present, leading to reduced drug efficacy.
D. Diverticulitis disease primarily affects the gastrointestinal system and would not directly influence the distribution of an antibiotic used to treat cellulitis in the leg.
Correct Answer is A
Explanation
A. A return to normal respiratory rate, rhythm, and depth is correct because opioid antagonists, such as naloxone, are primarily used to reverse the respiratory depression caused by opioid overdose.
B. Management of alcohol withdrawal symptoms is incorrect; opioid antagonists do not address alcohol withdrawal.
C. A reduction in the client's rating of their pain is incorrect; opioid antagonists counteract the effects of opioids, which can result in increased pain levels rather than reduction.
D. Alertness and improve memory function is incorrect; while opioid antagonists may improve alertness by reversing sedation, the primary goal focuses on restoring respiratory function.