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A nurse is teaching a patient newly diagnosed with Parkinson’s disease about the pathophysiology of the condition. Which of the following explanations best describes the underlying cause of Parkinson's disease?

A.

Inflammation of the motor cortex leads to decreased coordination and balance

B.

Degeneration of dopamine producing neurons in the substantia nigra of the brain leads to motor dysfunction

C.

A loss of acetylcholine in the brain leads to memory problems and cognitive decline.

D.

Excess production of dopamine in the basal ganglia leads to tremors and muscle rigidity.

Answer and Explanation

The Correct Answer is B

A. Inflammation of the motor cortex leads to decreased coordination and balance. Parkinson’s disease is not caused by inflammation in the motor cortex; it primarily involves the loss of dopamine-producing neurons.

 

B. Degeneration of dopamine-producing neurons in the substantia nigra of the brain leads to motor dysfunction. Parkinson’s disease is caused by the degeneration of dopamine-producing neurons in the substantia nigra, leading to motor symptoms such as tremors, rigidity, and bradykinesia.

 

C. A loss of acetylcholine in the brain leads to memory problems and cognitive decline. While a loss of acetylcholine is associated with Alzheimer’s disease, it is not the primary issue in Parkinson’s disease.

 

D. Excess production of dopamine in the basal ganglia leads to tremors and muscle rigidity. In Parkinson’s disease, there is a decrease, not an excess, in dopamine production, which contributes to motor symptoms.


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Correct Answer is C

Explanation

A. Encourage the client to walk on the injured ankle to promote circulation. Weight-bearing activities should be avoided initially after a Grade II sprain to prevent further injury.

B. Immerse the ankle in warm water immediately after the injury. Ice, rather than warmth, is recommended immediately following an injury to reduce swelling and inflammation.

C. Apply ice to the affected ankle for the first 24-72 hours. Applying ice for 24-72 hours helps reduce swelling and pain by causing vasoconstriction and controlling inflammation in the acute phase.

D. Perform deep tissue massage on the injured area to reduce pain. Massaging a newly sprained ankle can aggravate inflammation and cause additional tissue damage.

Correct Answer is D

Explanation

A. Hypotension: Patients with SIADH typically have fluid retention, which can lead to hypertension, not hypotension.

B. Dry mucous membranes: In SIADH, fluid retention is common, so mucous membranes are usually moist, not dry.

C. Increased thirst: While thirst can occur in various conditions, it is not a primary symptom of SIADH.

D. Confusion or altered mental status: Confusion or altered mental status may occur in SIADH due to hyponatremia from excessive water retention.

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