A nurse is teaching a patient newly diagnosed with Parkinson’s disease about the pathophysiology of the condition. Which of the following explanations best describes the underlying cause of Parkinson's disease?
Inflammation of the motor cortex leads to decreased coordination and balance
Degeneration of dopamine producing neurons in the substantia nigra of the brain leads to motor dysfunction
A loss of acetylcholine in the brain leads to memory problems and cognitive decline.
Excess production of dopamine in the basal ganglia leads to tremors and muscle rigidity.
The Correct Answer is B
A. Inflammation of the motor cortex leads to decreased coordination and balance. Parkinson’s disease is not caused by inflammation in the motor cortex; it primarily involves the loss of dopamine-producing neurons.
B. Degeneration of dopamine-producing neurons in the substantia nigra of the brain leads to motor dysfunction. Parkinson’s disease is caused by the degeneration of dopamine-producing neurons in the substantia nigra, leading to motor symptoms such as tremors, rigidity, and bradykinesia.
C. A loss of acetylcholine in the brain leads to memory problems and cognitive decline. While a loss of acetylcholine is associated with Alzheimer’s disease, it is not the primary issue in Parkinson’s disease.
D. Excess production of dopamine in the basal ganglia leads to tremors and muscle rigidity. In Parkinson’s disease, there is a decrease, not an excess, in dopamine production, which contributes to motor symptoms.
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Correct Answer is D
Explanation
A. Frequent urination. Frequent urination is not typically associated with Crohn’s disease, which primarily affects the gastrointestinal system.
B. Jaundice. Jaundice is related to liver or biliary system issues and is not a common symptom of Crohn’s disease.
C. Joint pain. While Crohn’s disease may be associated with extraintestinal symptoms, joint pain is not as common as gastrointestinal symptoms during an exacerbation.
D. Abdominal pain and cramping. Abdominal pain and cramping are common symptoms of Crohn’s disease, especially during flare-ups, due to inflammation in the digestive tract.
Correct Answer is B
Explanation
A. Conjunctivitis. Conjunctivitis generally presents with redness and discharge but does not cause elevated intraocular pressure, severe pain, or visual disturbances like halos.
B. Acute angle-closure glaucoma. Acute angle-closure glaucoma is characterized by sudden severe eye pain, blurred vision, halos around lights, nausea, and vomiting, along with elevated intraocular pressure and a cloudy cornea.
C. Retinal detachment. Retinal detachment may cause sudden vision loss or flashing lights but typically lacks pain, nausea, or vomiting, and does not affect intraocular pressure.
D. Migraine with aura. A migraine with aura may cause visual disturbances but does not present with eye pain, red eye, or elevated intraocular pressure.