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A nurse is teaching a patient newly diagnosed with Parkinson’s disease about the pathophysiology of the condition. Which of the following explanations best describes the underlying cause of Parkinson's disease?

A.

Inflammation of the motor cortex leads to decreased coordination and balance

B.

Degeneration of dopamine producing neurons in the substantia nigra of the brain leads to motor dysfunction

C.

A loss of acetylcholine in the brain leads to memory problems and cognitive decline.

D.

Excess production of dopamine in the basal ganglia leads to tremors and muscle rigidity.

Answer and Explanation

The Correct Answer is B

A. Inflammation of the motor cortex leads to decreased coordination and balance. Parkinson’s disease is not caused by inflammation in the motor cortex; it primarily involves the loss of dopamine-producing neurons.

 

B. Degeneration of dopamine-producing neurons in the substantia nigra of the brain leads to motor dysfunction. Parkinson’s disease is caused by the degeneration of dopamine-producing neurons in the substantia nigra, leading to motor symptoms such as tremors, rigidity, and bradykinesia.

 

C. A loss of acetylcholine in the brain leads to memory problems and cognitive decline. While a loss of acetylcholine is associated with Alzheimer’s disease, it is not the primary issue in Parkinson’s disease.

 

D. Excess production of dopamine in the basal ganglia leads to tremors and muscle rigidity. In Parkinson’s disease, there is a decrease, not an excess, in dopamine production, which contributes to motor symptoms.


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View Related questions

Correct Answer is C

Explanation

A. Frequent urination: Frequent urination is not associated with osteomyelitis, a bone infection.

B. Increased range of motion: Osteomyelitis typically causes pain and restricted movement, not increased range of motion.

C. Localized bone pain and tenderness: Osteomyelitis commonly presents with localized bone pain, tenderness, and possibly swelling due to infection.

D. Hyperpigmentation of the skin: Hyperpigmentation is not a typical sign of osteomyelitis.

Correct Answer is D

Explanation

A. I need to monitor the puncture site for signs of infection such as redness or swelling. Monitoring the puncture site is crucial for detecting any signs of infection or complications, which the patient should be aware of.

B. I should follow a heart-healthy diet to support my recovery. A heart-healthy diet is recommended to manage cholesterol levels and prevent further coronary artery disease progression.

C. I will take my prescribed medications as directed by my doctor. Following the medication regimen is important for preventing complications and supporting recovery, especially for blood thinners or other cardiac medications.

D. I can resume my regular physical activities immediately after I get home. This statement indicates a need for further teaching, as patients should gradually resume physical activities and avoid strenuous activities immediately after PTCA to prevent complications, such as bleeding at the catheter insertion site.

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