A nurse is teaching a group of nurses about the administration of nitroglycerin. Which of the following routes of administration has the most rapid onset for the client?
Topical ointment
Sublingual
Transdermal patch
Sustained-release
The Correct Answer is B
A. Topical ointment has a slower onset as it must be absorbed through the skin before it can exert its effects.
B. Sublingual nitroglycerin provides rapid relief of angina symptoms because it is absorbed quickly into the bloodstream through the mucous membranes in the mouth, allowing for an immediate effect.
C. Transdermal patches release nitroglycerin slowly over time, leading to a delayed onset of action.
D. Sustained-release formulations are designed for prolonged effects rather than rapid onset, making them slower to take effect compared to sublingual administration.
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Correct Answer is B
Explanation
A. Folic acid does not specifically lower blood glucose; rather, it is primarily involved in DNA synthesis and cell division.
B. Folic acid is essential during pregnancy as it significantly reduces the risk of neural tube defects, such as spina bifida and anencephaly, in the developing fetus, making it a critical nutrient for pregnant women.
C. Folic acid does not prevent celiac disease; rather, celiac disease is an autoimmune disorder related to gluten intake.
D. While some studies suggest that folic acid may have a role in reducing the frequency of migraines, it is not a primary indication during pregnancy.
Correct Answer is C
Explanation
A. A history of hypertension is not a direct contraindication for propofol, although it should be monitored as part of overall management.
B. Benzodiazepine abuse/dependence does not contraindicate the use of propofol but may require careful assessment of sedation and anesthesia needs.
C. Propofol contains soy lecithin and egg phosphatide, making allergies to these products a significant contraindication, as they can lead to severe allergic reactions.
D. An allergy to latex is not a contraindication for propofol use but should be addressed in the overall anesthesia plan regarding equipment and supplies.