A nurse is teaching a group of nurses about the administration of nitroglycerin. Which of the following routes of administration has the most rapid onset for the client?
Topical ointment
Sublingual
Transdermal patch
Sustained-release
The Correct Answer is B
A. Topical ointment has a slower onset as it must be absorbed through the skin before it can exert its effects.
B. Sublingual nitroglycerin provides rapid relief of angina symptoms because it is absorbed quickly into the bloodstream through the mucous membranes in the mouth, allowing for an immediate effect.
C. Transdermal patches release nitroglycerin slowly over time, leading to a delayed onset of action.
D. Sustained-release formulations are designed for prolonged effects rather than rapid onset, making them slower to take effect compared to sublingual administration.
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Correct Answer is ["B","C","E","F"]
Explanation
A. Bruising is typically related to anticoagulant effects or blood disorders and not directly tied to the desired effects of PTU.
B. Improved sleep is an indicator that hyperthyroidism symptoms, such as insomnia, are being managed effectively.
C. A decrease in anxiety can suggest effective management of hyperthyroidism, as anxiety is a common symptom of this condition.
D. Weight loss or inability to gain weight is usually a symptom of hyperthyroidism, so this statement would indicate that PTU is not achieving the desired effect.
E. A return to regular menstruation can indicate improved thyroid function, as hyperthyroidism can disrupt menstrual cycles.
F. Reduced heart rate and the absence of palpitations suggest effective management of hyperthyroidism symptoms, indicating the drug is having the desired effect.
Correct Answer is D
Explanation
A. Prophylactic therapy is used to prevent infection in at-risk individuals, not to treat suspected infections before confirming lab results.
B. Palliative therapy is intended for symptom relief, often in cases where curing the disease is not the goal.
C. Maintenance therapy is designed to maintain health stability rather than to treat suspected infections without lab confirmation.
D. Empiric therapy involves starting treatment based on clinical judgment before lab results are available. This approach is useful to manage infections promptly when waiting for cultures could delay necessary care.