A nurse is teaching a client who is beginning highly active antiretroviral therapy (HAART) for HIV which includes zidovudine. The nurse should include teaching regarding which black box warning associated with this medication?
lactic acidosis
Uterine cancer
oral candidiasis
thromboembolic events
The Correct Answer is A
A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.
B. Uterine Cancer: Zidovudine is not associated with uterine cancer.
C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.
D. Thromboembolic Events: This is not a known black box warning for zidovudine.
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Correct Answer is A
Explanation
A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.
B. Uterine Cancer: Zidovudine is not associated with uterine cancer.
C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.
D. Thromboembolic Events: This is not a known black box warning for zidovudine.
Correct Answer is ["A","C","D","E"]
Explanation
A. Measles: The measles vaccine is a live-attenuated vaccine, which contains a weakened form of the virus and should be avoided in immunocompromised clients due to the risk of infection.
B. Inactivated Polio: The inactivated polio vaccine (IPV) is not a live vaccine, as it uses killed virus, making it safe for immunocompromised clients.
C. Mumps: The mumps vaccine is a live-attenuated vaccine and is part of the MMR (measles, mumps, rubella) vaccine. It should be avoided in clients with weakened immune systems.
D. Varicella: The varicella (chickenpox) vaccine is a live-attenuated vaccine. It should not be given to immunocompromised clients due to the potential risk of severe infection.
E. Rubella: The rubella vaccine is also a live-attenuated vaccine, included in the MMR vaccine, and is contraindicated in immunocompromised individuals.