A nurse is teaching a client who is beginning highly active antiretroviral therapy (HAART) for HIV which includes zidovudine. The nurse should include teaching regarding which black box warning associated with this medication?
lactic acidosis
Uterine cancer
oral candidiasis
thromboembolic events
The Correct Answer is A
A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.
B. Uterine Cancer: Zidovudine is not associated with uterine cancer.
C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.
D. Thromboembolic Events: This is not a known black box warning for zidovudine.
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Correct Answer is C
Explanation
A. Amoxicillin/clavulanate (Augmentin): Amoxicillin/clavulanate is a broad-spectrum antibiotic but not the preferred choice for anthrax exposure.
B. Nystatin (Mycostatin): Nystatin is an antifungal medication used for treating fungal infections, such as oral thrush or cutaneous candidiasis. It is not effective against anthrax, which is a bacterial infection.
C. Ciprofloxacin (Cipro): Ciprofloxacin, a fluoroquinolone, is the recommended first-line antibiotic for treating anthrax exposure due to its efficacy against Bacillus anthracis, the bacteria causing anthrax.
D. Tamoxifen: Tamoxifen is a selective estrogen receptor modulator (SERM) used primarily in the treatment of breast cancer. It has no role in treating bacterial infections like anthrax.
Correct Answer is B
Explanation
A. Medications will need to be taken until the Mantoux test is negative: The Mantoux test (PPD) is used for diagnosis, not for monitoring treatment efficacy.
B. A typical course of treatment usually involves 6 months of consistent medication use. TB treatment typically requires at least 6 months of consistent medication adherence to fully eradicate the bacteria and prevent resistance.
C. Medications will need to be taken for the rest of the client's life, even if the client feels better: This is inaccurate. TB treatment is time-limited, though the full course must be completed.
D. The client's family will also need to take medications to prevent infection: Prophylactic treatment is not usually required for all family members, though they may need screening.