A nurse is teaching a class about medication interactions.
The nurse should include that iron preparations should be administered with which of the following?
Cheese.
Antacids containing magnesium.
Orange juice.
Milk.
The Correct Answer is C
Choice A rationale
Cheese is high in calcium, which can interfere with the absorption of iron by binding to it in the digestive tract, making it less available for absorption.
Choice B rationale
Antacids containing magnesium can interfere with the absorption of iron by increasing the pH of the stomach, reducing the solubility and absorption of iron.
Choice C rationale
Orange juice is high in vitamin C, which can enhance the absorption of iron by reducing it to a form that is more easily absorbed by the body.
Choice D rationale
Milk contains calcium, which can inhibit the absorption of iron. Calcium competes with iron for absorption in the intestines, leading to reduced iron absorption.
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Correct Answer is D
Explanation
Choice D rationale
Intravenous (IV) administration has the fastest rate of absorption because the medication is delivered directly into the bloodstream, bypassing the absorption barriers of the digestive
system or muscle tissue. This ensures rapid onset of action.
Choice A rationale
Enteral administration involves the gastrointestinal tract, including oral and feeding tube methods. Absorption is slower as the medication passes through the digestive system before
entering the bloodstream.
Choice B rationale
Intramuscular (IM) administration involves injecting the medication into muscle tissue, where it is absorbed into the bloodstream. Absorption is quicker than enteral routes but slower
compared to IV administration.
Choice C rationale
Topical administration involves applying medication to the skin or mucous membranes. Absorption is generally slower and is intended for local or systemic effects, depending on the medication.
Correct Answer is C
Explanation
Choice A rationale
Toxic levels refer to concentrations of a medication that are high enough to cause harmful effects or poisoning. This is not related to the lowest serum concentration.
Choice B rationale
Peak levels are the highest concentration of a medication in the bloodstream after administration. This occurs after the drug is absorbed and distributed.
Choice C rationale
Trough levels occur when the medication is at its lowest concentration in the bloodstream, typically just before the next dose is due. Monitoring trough levels helps ensure therapeutic effectiveness while avoiding toxicity.
Choice D rationale
Half-life refers to the time it takes for the concentration of a drug in the bloodstream to decrease by half. It is not directly related to the lowest serum concentration at a specific point in time.