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A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?

A.

Ondansetron

B.

Diphenhydramine

C.

Gentamicin

D.

Omeprazole

Answer and Explanation

The Correct Answer is C

Rationale:

 

A. Ondansetron is an antiemetic that does not typically cause nephrotoxicity and is generally safe for use in clients with chronic kidney disease.

 

B. Diphenhydramine is an antihistamine that does not have nephrotoxic effects and is commonly used for allergy symptoms or as a sleep aid.

 

C. Gentamicin is an aminoglycoside antibiotic that is known to be nephrotoxic, especially in clients with pre-existing kidney disease. It requires careful monitoring of kidney function and dosing adjustments to prevent kidney damage.

 

D. Omeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD) and does not typically cause nephrotoxicity, although long-term use has been associated with an increased risk of chronic kidney disease.


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View Related questions

Correct Answer is B

Explanation

Rationale:

A. Drowsiness is not typically associated with thyrotoxicosis; rather, clients are more likely to experience restlessness or insomnia.

B. Heat intolerance is a common symptom of thyrotoxicosis, reflecting the increased metabolic rate associated with excessive thyroid hormone levels.

C. Bradycardia is associated with hypothyroidism, not thyrotoxicosis. In thyrotoxicosis, tachycardia or palpitations are more likely.

D. Dry skin is a symptom of hypothyroidism, whereas in thyrotoxicosis, the skin may become warm, moist, and flushed.

Correct Answer is ["A","C","D","E"]

Explanation

Rationale:

A. Reducing cholesterol and saturated fat intake is important for managing cardiovascular health, which is crucial for clients with diabetes to prevent complications such as heart disease and stroke.

B. Sustaining hyperglycemia is incorrect; it actually contributes to complications like neuropathy, retinopathy, and nephropathy. The goal is to maintain blood glucose levels within the target range.

C. Maintaining optimal blood pressure is essential in preventing diabetic nephropathy, as high blood pressure can damage the kidneys and worsen diabetic kidney disease.

D. Increasing physical activity helps improve insulin sensitivity, control blood glucose levels, and reduce the risk of complications associated with diabetes.

E. Smoking cessation is critical in reducing the risk of cardiovascular disease, which is higher in clients with diabetes. Smoking can exacerbate the complications of diabetes.

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