A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?
Ondansetron
Diphenhydramine
Gentamicin
Omeprazole
The Correct Answer is C
Rationale:
A. Ondansetron is an antiemetic that does not typically cause nephrotoxicity and is generally safe for use in clients with chronic kidney disease.
B. Diphenhydramine is an antihistamine that does not have nephrotoxic effects and is commonly used for allergy symptoms or as a sleep aid.
C. Gentamicin is an aminoglycoside antibiotic that is known to be nephrotoxic, especially in clients with pre-existing kidney disease. It requires careful monitoring of kidney function and dosing adjustments to prevent kidney damage.
D. Omeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD) and does not typically cause nephrotoxicity, although long-term use has been associated with an increased risk of chronic kidney disease.
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Correct Answer is D
Explanation
Rationale:
A. Levofloxacin is an antibiotic used to treat bacterial infections, not hypothyroidism.
B. Radioactive iodine is used to treat hyperthyroidism by reducing thyroid hormone production, not hypothyroidism.
C. Sumatriptan is a medication used to treat migraines, not hypothyroidism.
D. Levothyroxine is the standard treatment for hypothyroidism. It is a synthetic form of the thyroid hormone thyroxine (T4) and helps to normalize thyroid function by supplementing the hormone that the thyroid gland is not producing adequately.
Correct Answer is ["A","B","C","D","E","F"]
Explanation
Rationale:
A: Inhale deeply and then exhale completely: This step helps to empty the lungs, making room for the medication to be inhaled effectively.
B: Place her lips firmly around the mouthpiece: Ensuring a tight seal around the mouthpiece prevents the medication from escaping and ensures proper delivery to the lungs.
C: Breathe in deeply over 2 to 3 seconds while pushing down on the canister: Coordinating the inhalation with the activation of the canister ensures that the medication is inhaled deeply into the lungs.
D: Hold her breath for 10 seconds: Holding the breath allows the medication to settle in the lungs and increase its effectiveness.
E: Exhale slowly through pursed lips: This helps to maintain the medication in the lungs for as long as possible and promotes better absorption.
F: Wait 60 seconds between each puff: Waiting between puffs allows time for the medication to take effect and ensures that the next dose will be more effective.
