A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?
Ondansetron
Diphenhydramine
Gentamicin
Omeprazole
The Correct Answer is C
Rationale:
A. Ondansetron is an antiemetic that does not typically cause nephrotoxicity and is generally safe for use in clients with chronic kidney disease.
B. Diphenhydramine is an antihistamine that does not have nephrotoxic effects and is commonly used for allergy symptoms or as a sleep aid.
C. Gentamicin is an aminoglycoside antibiotic that is known to be nephrotoxic, especially in clients with pre-existing kidney disease. It requires careful monitoring of kidney function and dosing adjustments to prevent kidney damage.
D. Omeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD) and does not typically cause nephrotoxicity, although long-term use has been associated with an increased risk of chronic kidney disease.
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Correct Answer is C
Explanation
Rationale:
A. An increase in weight is typically a symptom of untreated or poorly managed hypothyroidism, not a therapeutic response.
B. A decrease in body temperature is associated with hypothyroidism, and an improvement in this condition should result in a normalization of temperature, not a decrease.
C. An increase in energy is a therapeutic response to liothyronine, as hypothyroidism often causes fatigue and low energy levels. Treatment with liothyronine should alleviate these symptoms and restore normal energy levels.
D. A decreased heart rate (bradycardia) is a symptom of hypothyroidism, and effective treatment should normalize the heart rate, not lower it further.
Correct Answer is C
Explanation
Rationale:
A. Discomfort at the puncture site is expected after a thoracentesis and typically managed with analgesics.
B. A decreased temperature is not a common complication of thoracentesis and might indicate other issues, but it is not immediately alarming.
C. An increased heart rate (tachycardia) could be a sign of a pneumothorax, hemorrhage, or other serious complications following thoracentesis. This requires immediate assessment and intervention.
D. Serosanguineous drainage is expected to some extent, but it should be monitored for changes that might indicate a complication such as infection or continued bleeding.