A nurse is reviewing the medical history of a client who has myasthenia gravis and is asking about starting neostigmine. The nurse should identify which of the following client conditions as a potential contraindication for cholinesterase inhibitor therapy?
Cataracts
Hypertension
Hypothyroidism
Peptic ulcer disease
The Correct Answer is D
Rationale:
A. Cataracts are not a contraindication for cholinesterase inhibitors like neostigmine.
B. Hypertension is not a direct contraindication for cholinesterase inhibitor therapy, although caution may be exercised depending on the overall health status of the client.
C. Hypothyroidism is not contraindicated for cholinesterase inhibitors; however, it should be managed appropriately.
D. Peptic ulcer disease is a significant contraindication for cholinesterase inhibitors like neostigmine because these medications can increase gastric secretions and motility, potentially exacerbating ulcer conditions and leading to complications.
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View Related questions
Correct Answer is ["A","D","E"]
Explanation
Rationale:
A. Blurred vision is a common side effect of anticholinergic medications due to their effect on the eye muscles and pupil dilation.
B. Polyuria is not typically associated with anticholinergic medications; these medications may actually lead to urinary retention.
C. A productive cough is not an expected adverse effect of anticholinergic medications; instead, they may cause dry mucous membranes and a dry cough.
D. Tachycardia can occur as anticholinergic medications block the effects of acetylcholine on the heart, leading to increased heart rate.
E. Constipation is a well-known side effect of anticholinergic medications because they reduce gastrointestinal motility.
Correct Answer is C
Explanation
Rationale:
A. Muscle rigidity of the extremities: This finding is more indicative of hyperkalemia or severe electrolyte imbalances but is not a common symptom of hypokalemia.
B. Bounding radial pulses: This finding is more associated with hypervolemia or hyperkalemia, not with hypokalemia caused by furosemide.
C. Depressed deep tendon reflexes: This is the correct response, as low potassium levels (hypokalemia) can lead to diminished reflexes due to its role in neuromuscular function.
D. Increased bowel motility: This is incorrect, as hypokalemia typically results in decreased bowel motility and may cause constipation rather than increased motility.