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A nurse is reviewing the medical history of a client who has myasthenia gravis and is asking about starting neostigmine. The nurse should identify which of the following client conditions as a potential contraindication for cholinesterase inhibitor therapy?

A.

Cataracts

B.

Hypertension

C.

Hypothyroidism

D.

Peptic ulcer disease

Answer and Explanation

The Correct Answer is D

Rationale:

 

A. Cataracts are not a contraindication for cholinesterase inhibitors like neostigmine.

 

B. Hypertension is not a direct contraindication for cholinesterase inhibitor therapy, although caution may be exercised depending on the overall health status of the client.

 

C. Hypothyroidism is not contraindicated for cholinesterase inhibitors; however, it should be managed appropriately.

 

D. Peptic ulcer disease is a significant contraindication for cholinesterase inhibitors like neostigmine because these medications can increase gastric secretions and motility, potentially exacerbating ulcer conditions and leading to complications.

 


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View Related questions

Correct Answer is C

Explanation

Rationale:

A. Delaying the incident report until the end of the current shift can compromise the timely documentation of the error and any necessary interventions that may arise.

B. While it's important to notify risk management, the priority should be to document the incident immediately after assessing the client to ensure a complete record of the error.

C. Completing the incident report as soon as the assessment is complete is the most appropriate action, allowing for prompt documentation of the error and any potential effects on patient care.

D. Informing the previous nurse is necessary for communication, but it should not delay the completion of the incident report, which is crucial for tracking errors and improving safety protocols.

Correct Answer is B

Explanation

Rationale:

A. Hydrochlorothiazide does not prevent angiotensin II from binding with receptor sites; this action is typically associated with ACE inhibitors or angiotensin receptor blockers.

B. Hydrochlorothiazide decreases the reabsorption of sodium and water in the distal renal tubule, which leads to increased urine output and decreased blood volume, effectively lowering blood pressure.

C. Hydrochlorothiazide does not block beta receptors; this is the mechanism of action for beta-blockers.

D. Hydrochlorothiazide does not promote the movement of extravascular fluids into the vascular compartment; instead, it reduces blood volume by promoting diuresis.

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