A nurse is providing teaching to a client who has prostate cancer and a new prescription for leuprolide. The nurse should explain to the client that leuprolide treats prostate cancer by which of the following actions?
"Leuprolide decreases the production of testosterone."
"Leuprolide kills cells at all stages of cellular division."
"Leuprolide increases estrogen levels in your body to counteract the cancer cells."
"Leuprolide suppresses the pituitary gland's production of growth hormone to decrease cancer cellular growth."
The Correct Answer is A
Rationale:
A. "Leuprolide decreases the production of testosterone.": Leuprolide is a gonadotropin-releasing hormone (GnRH) agonist that works by reducing testosterone production, which is essential for the growth of prostate cancer cells. This mechanism slows the progression of the cancer.
B. "Leuprolide kills cells at all stages of cellular division.": This describes how chemotherapy drugs work, but leuprolide does not function by directly killing cancer cells at different stages of their division.
C. "Leuprolide increases estrogen levels in your body to counteract the cancer cells.": Leuprolide does not increase estrogen levels. Instead, it reduces testosterone levels, which is more effective in managing prostate cancer.
D. "Leuprolide suppresses the pituitary gland's production of growth hormone to decrease cancer cellular growth.": Leuprolide suppresses the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), not growth hormone, to decrease testosterone levels.
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Correct Answer is C
Explanation
Rationale:
A. Magnesium 2.5 mEq/L: A magnesium level slightly above the normal range does not indicate an immediate need to discontinue clozapine, as this level is not related to the adverse effects of the drug.
B. Potassium 5.4 mEq/L: While elevated potassium levels can pose a health risk, this is not a direct indicator to discontinue clozapine. Potassium levels can be managed with other interventions.
C. WBC 2,500/mm³: Clozapine carries a risk of agranulocytosis, a condition where the white blood cell (WBC) count becomes dangerously low, leading to severe infection risk. A WBC count of 2,500/mm³ is below the normal range and indicates the need to discontinue clozapine immediately.
D. Sodium 134 mEq/L: A slightly low sodium level is not typically related to clozapine use and does not warrant discontinuation of the medication.
Correct Answer is A, B, C, D, E
Explanation
Rationale:
- Administering albuterol first is crucial because it is a bronchodilator that will help open the airways before administering the anti-inflammatory fluticasone.
- The client should rest for 1 minute between puffs of albuterol to allow for the medication to take effect.
- After taking the second puff of albuterol, a longer rest of 5 minutes allows the client to experience the full effects of the bronchodilator.
- Finally, administering fluticasone afterward will help reduce inflammation in the airways, maximizing the benefit of both medications.