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A nurse is providing teaching to a client who has erectile dysfunction and has a new prescription for tadalafil. Which of the following client statements indicates an understanding of the teaching?

A.

I should crush this medication if I have difficulty swallowing.

B.

This medication can decrease my blood pressure.

C.

I can take this medication up to twice a day.

D.

The effects of this medication will not last more than 4 hours.

Answer and Explanation

The Correct Answer is B

Choice A rationale

 

Crushing tadalafil is not recommended as it can alter the medication’s effectiveness and absorption. Tadalafil should be taken whole to ensure proper dosage and efficacy.

 

Choice B rationale

 

Tadalafil can decrease blood pressure by relaxing blood vessels, which allows for increased blood flow. This is a known effect of phosphodiesterase type 5 (PDE5) inhibitors like tadalafil.

 

Choice C rationale

 

Tadalafil should not be taken more than once a day. Taking it twice a day can increase the risk of side effects and is not recommended.

 

Choice D rationale

 

The effects of tadalafil can last up to 36 hours, not just 4 hours. This prolonged duration is one of the reasons it is preferred by some patients.


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Correct Answer is D

Explanation

Choice A rationale

Sitagliptin is a DPP-4 inhibitor used to manage blood sugar levels in type 2 diabetes but does not specifically slow the progression of nephropathy.

Choice B rationale

Glipizide is a sulfonylurea that helps control blood sugar levels but does not have a direct effect on slowing nephropathy progression.

Choice C rationale

Metoprolol is a beta-blocker used to manage hypertension but does not specifically target nephropathy progression.

Choice D rationale

Losartan is an angiotensin II receptor blocker (ARB) that helps manage hypertension and has been shown to slow the progression of nephropathy in patients with type 2 diabetes.

Correct Answer is C

Explanation

Choice A rationale

Rifampin is an antibiotic used to treat tuberculosis and other bacterial infections. It does not have a known interaction with St. John’s wort.

Choice B rationale

Furosemide is a diuretic used to treat fluid retention and high blood pressure. It does not have a known interaction with St. John’s wort.

Choice C rationale

Citalopram is a selective serotonin reuptake inhibitor (SSRI) used to treat depression. St. John’s wort can interact with SSRIs like citalopram, potentially leading to serotonin syndrome, a serious condition caused by excessive levels of serotonin in the brain.

Choice D rationale

Allopurinol is used to treat gout and kidney stones. It does not have a known interaction with St. John’s wort.

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