A nurse is caring for a patient with acne who has been prescribed tetracycline. The patient states that they drink a glass of milk every morning with breakfast. What is the nurse's best response?
"Milk helps the medication absorb more quickly."
"You should avoid milk and dairy products when taking tetracycline, as they reduce its effectiveness."
"It is safe to take milk with tetracycline, as long as you increase your water intake."
"It is fine to drink milk if taken at least 1 hour before or 2 hours after."
The Correct Answer is B
A. Milk does not enhance the absorption of tetracycline; rather, it contains calcium, which can bind to the antibiotic and reduce its absorption.
B. Avoiding milk and dairy products while taking tetracycline is essential as they reduce the medication's effectiveness by forming insoluble complexes with the drug.
C. Taking milk with tetracycline is not safe due to the risk of decreased absorption; simply increasing water intake does not negate this interaction.
D. While spacing the intake of milk and tetracycline might seem beneficial, it is best to avoid dairy entirely during the treatment to ensure maximum efficacy of the medication.
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Correct Answer is C
Explanation
A. Hypertension can affect drug distribution to some extent due to altered perfusion but is not the most significant factor impacting distribution, especially for a local condition like cellulitis.
B. Liver dysfunction primarily affects the metabolism and clearance of drugs rather than their distribution, although it may indirectly influence distribution by altering protein binding.
C. Peripheral vascular disease significantly impacts blood flow to the extremities, which can hinder the distribution of the antibiotic to the affected area (the left leg) where the cellulitis is present, leading to reduced drug efficacy.
D. Diverticulitis disease primarily affects the gastrointestinal system and would not directly influence the distribution of an antibiotic used to treat cellulitis in the leg.
Correct Answer is B
Explanation
A. Prothrombin time (PT) is used to monitor warfarin therapy, not heparin therapy.
B. Activated partial thromboplastin time (aPTT) is the primary laboratory test used to assess the effectiveness of heparin therapy, measuring the time it takes for blood to clot and ensuring therapeutic levels.
C. The International normalized ratio (INR) is also related to warfarin therapy rather than heparin.
D. Serum potassium level is not relevant for assessing heparin therapy but may be monitored for other reasons.