A nurse is caring for a patient with acne who has been prescribed tetracycline. The patient states that they drink a glass of milk every morning with breakfast. What is the nurse's best response?
"Milk helps the medication absorb more quickly."
"You should avoid milk and dairy products when taking tetracycline, as they reduce its effectiveness."
"It is safe to take milk with tetracycline, as long as you increase your water intake."
"It is fine to drink milk if taken at least 1 hour before or 2 hours after."
The Correct Answer is B
A. Milk does not enhance the absorption of tetracycline; rather, it contains calcium, which can bind to the antibiotic and reduce its absorption.
B. Avoiding milk and dairy products while taking tetracycline is essential as they reduce the medication's effectiveness by forming insoluble complexes with the drug.
C. Taking milk with tetracycline is not safe due to the risk of decreased absorption; simply increasing water intake does not negate this interaction.
D. While spacing the intake of milk and tetracycline might seem beneficial, it is best to avoid dairy entirely during the treatment to ensure maximum efficacy of the medication.
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Correct Answer is ["A","B"]
Explanation
A. The client's skin and eyes are visibly jaundiced is correct because jaundice indicates a buildup of bilirubin in the blood, which is a sign of liver dysfunction.
B. The client's AST and ALT levels are elevated is correct because elevated levels of these liver enzymes indicate hepatocellular injury, which is consistent with liver damage due to acetaminophen overdose.
C. The client's temperature is 102.5° F (39.2° C) is incorrect; while a fever can occur in various conditions, it is not specific for liver damage in this context.
D. The client has an elevated red blood cell count is incorrect; elevated red blood cell counts are not indicative of liver damage and may be related to other factors.
E. The client's eyes are sensitive to light is incorrect; photophobia is not a direct indicator of liver damage and is more related to other conditions.
Correct Answer is C
Explanation
A. Hypertension can affect drug distribution to some extent due to altered perfusion but is not the most significant factor impacting distribution, especially for a local condition like cellulitis.
B. Liver dysfunction primarily affects the metabolism and clearance of drugs rather than their distribution, although it may indirectly influence distribution by altering protein binding.
C. Peripheral vascular disease significantly impacts blood flow to the extremities, which can hinder the distribution of the antibiotic to the affected area (the left leg) where the cellulitis is present, leading to reduced drug efficacy.
D. Diverticulitis disease primarily affects the gastrointestinal system and would not directly influence the distribution of an antibiotic used to treat cellulitis in the leg.