A nurse is caring for a patient with acne who has been prescribed tetracycline. The patient states that they drink a glass of milk every morning with breakfast. What is the nurse's best response?
"Milk helps the medication absorb more quickly."
"You should avoid milk and dairy products when taking tetracycline, as they reduce its effectiveness."
"It is safe to take milk with tetracycline, as long as you increase your water intake."
"It is fine to drink milk if taken at least 1 hour before or 2 hours after."
The Correct Answer is B
A. Milk does not enhance the absorption of tetracycline; rather, it contains calcium, which can bind to the antibiotic and reduce its absorption.
B. Avoiding milk and dairy products while taking tetracycline is essential as they reduce the medication's effectiveness by forming insoluble complexes with the drug.
C. Taking milk with tetracycline is not safe due to the risk of decreased absorption; simply increasing water intake does not negate this interaction.
D. While spacing the intake of milk and tetracycline might seem beneficial, it is best to avoid dairy entirely during the treatment to ensure maximum efficacy of the medication.
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Correct Answer is A
Explanation
A. Try not to swallow while the pill dissolves is correct because sublingual medications are designed to be absorbed directly into the bloodstream through the mucous membranes under the tongue, and swallowing may hinder this absorption.
B. Take a big drink of water and swallow the pill is incorrect because sublingual medications should not be swallowed with water as they need to dissolve under the tongue.
C. Swallow frequently to get the best benefit is incorrect, as this can interfere with the absorption of the medication.
D. Chew the pill so it will dissolve faster is incorrect since chewing may destroy the sublingual formulation, preventing it from working as intended.
Correct Answer is A
Explanation
A. A reduced plasma albumin level can lead to increased free drug levels in the bloodstream, raising the risk of drug toxicity, particularly for highly protein-bound medications.
B. Decreased therapeutic effects are less likely because the decrease in albumin can lead to higher free drug concentrations, which may actually increase effects rather than decrease them.
C. Altered drug absorption is generally not directly influenced by plasma albumin levels; it relates more to gastrointestinal factors.
D. Increased drug metabolism is not a direct consequence of lower albumin levels; instead, the concern is primarily about increased free drug concentrations and potential toxicity.