A nurse is caring for a client with Cushing's syndrome. Which assessment findings would the nurse expect? (Select all that apply.)
Purple striae
Moon face
Bronze pigmentation
Buffalo hump
Poor wound healing
Correct Answer : A,B,D,E
Rationale:
A. Purple striae (stretch marks) are common in Cushing's syndrome due to skin thinning and the redistribution of fat.
B. A "moon face" is a classic sign of Cushing's syndrome, caused by fat deposition in the face.
C. Bronze pigmentation is associated with Addison's disease, not Cushing's syndrome.
D. A "buffalo hump," or fat accumulation on the upper back, is another characteristic feature of Cushing's syndrome.
E. Poor wound healing is expected in Cushing's syndrome due to the effects of prolonged exposure to high cortisol levels, which impair immune function and tissue repair.
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Correct Answer is C
Explanation
Rationale:
A. Hypernatremia, an elevated sodium level, does not cause Trousseau's or Chvostek's signs.
B. Hypermagnesemia, an elevated magnesium level, is not associated with positive Trousseau's and Chvostek's signs.
C. Hypocalcemia, a low calcium level, is commonly associated with positive Trousseau's and Chvostek's signs. Trousseau's sign is a carpopedal spasm induced by inflating a blood pressure cuff, while Chvostek's sign is facial twitching in response to tapping over the facial nerve. Both are indicative of neuromuscular irritability due to low calcium levels.
D. Hypokalemia, a low potassium level, does not cause these specific signs and is associated with different clinical manifestations.
Correct Answer is C
Explanation
Rationale:
A. Coffee does not interact with glimepiride.
B. Milk is not contraindicated with glimepiride.
C. Alcohol should be avoided while taking glimepiride, as it can potentiate the hypoglycemic effects of the medication and may increase the risk of a severe drop in blood sugar levels.
D. Grapefruit juice is not known to have a significant interaction with glimepiride.