A nurse is caring for a client who recently traveled to a malaria-stricken country. The client is diagnosed with malaria and is prescribed chloroquine (Aralen). Which of the following adverse effects should the nurse educate the client regarding this medication?
Retinal toxicity
Tumors
Pancytopenia
Cancer
The Correct Answer is A
A. Retinal toxicity: Chloroquine is associated with retinal toxicity, which can lead to vision changes or damage. Regular eye exams are necessary to monitor for early signs of toxicity.
B. Tumors: Chloroquine is not associated with the development of tumors.
C. Pancytopenia: This refers to a reduction in all blood cells and is not a known adverse effect of chloroquine.
D. Cancer: Chloroquine is not linked to an increased risk of cancer.
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Correct Answer is B
Explanation
A. Thromboembolic events: This is not a black box warning for ciprofloxacin.
B. This drug has a black box warning for causing tendon rupture: Ciprofloxacin, a fluoroquinolone, has a black box warning for the risk of tendonitis and tendon rupture, especially in older adults or those on corticosteroids.
C. Endometrial cancers: Ciprofloxacin is not associated with cancer.
D. Breast cancer: There is no link between ciprofloxacin and breast cancer.
Correct Answer is D
Explanation
A. Macrolides: Macrolides, such as azithromycin or erythromycin, are often used as alternatives in clients with a penicillin allergy, as they do not have a beta-lactam ring and generally do not cause cross-reactivity.
B. Antiretrovirals: Antiretrovirals are used for treating HIV/AIDS and are unrelated to penicillin antibiotics, with no cross-sensitivity concerns.
C. Antimalarials: Antimalarial drugs are used to treat malaria and are not related to penicillin antibiotics, so they would not be a concern for cross-sensitivity.
D. Cephalosporins: Cephalosporins have a beta-lactam structure similar to penicillins, which can sometimes cause cross-reactivity in clients with a penicillin allergy. However, the risk is lower with newer generations.