A nurse is caring for a client who overdosed on morphine and has a respiratory rate of 6/min. Which medication should the nurse plan to administer?
Epinephrine
Protamine
Flumazenil
Naloxone
The Correct Answer is D
A. Epinephrine is primarily used for anaphylaxis and severe asthma attacks; it is not effective in reversing opioid overdose.
B. Protamine is an antidote for heparin, not for opioid overdose.
C. Flumazenil is a benzodiazepine antagonist and is not indicated for opioid overdose; it can potentially precipitate seizures in patients with mixed drug overdoses.
D. Naloxone is an opioid antagonist specifically indicated for reversing the effects of opioid overdose, including respiratory depression, making it the appropriate choice in this scenario.
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Correct Answer is A
Explanation
A. Nystatin is an antifungal medication used to treat oral candidiasis (thrush), which is consistent with the client's symptoms of soreness in the mouth and the presence of a white, milky plaque that does not rub off.
B. Amoxicillin is an antibiotic that treats bacterial infections but would not be effective against fungal infections like oral thrush.
C. Metronidazole is an antibiotic and antiprotozoal medication, which is not appropriate for treating oral candidiasis.
D. Acyclovir is an antiviral medication used to treat infections caused by certain viruses, such as herpes, and is not effective for fungal infections like thrush.
Correct Answer is C
Explanation
A. Macrolides, such as azithromycin and erythromycin, have a low cross-reactivity with penicillin and are typically safe alternatives for those with penicillin allergies.
B. Sulfonamides are not structurally similar to penicillins and generally do not have cross-sensitivity issues with penicillin allergies.
C. Cephalosporins share a similar beta-lactam structure to penicillins, which can result in cross-sensitivity in some individuals with a penicillin allergy. For this reason, they should be avoided or used with caution in these clients.
D. Tetracyclines have a different structure from penicillins and are usually safe for clients with penicillin allergies.