A nurse is caring for a client who is taking enalapril (Vasotec). Which of the following outcomes indicates a therapeutic effect of the medication?
Increase of high-density lipoproteins.
Decreased pain from intermittent claudication.
Decreased blood pressure
Decrease in low density lipoproteins.
The Correct Answer is C
A) Increase of high-density lipoproteins: While higher levels of high-density lipoproteins (HDL) are generally associated with a lower risk of cardiovascular disease, enalapril is not primarily used to target lipid levels. Its main purpose is to manage blood pressure and reduce the risk of heart failure and renal complications, rather than specifically affecting HDL levels.
B) Decreased pain from intermittent claudication: Intermittent claudication is typically related to peripheral artery disease, which may not be directly improved by enalapril. While managing blood pressure can indirectly benefit circulation, enalapril is not indicated specifically for alleviating pain associated with claudication.
C) Decreased blood pressure: Enalapril is an ACE inhibitor used primarily to treat hypertension. A significant decrease in blood pressure is a direct therapeutic effect of the medication, indicating that it is effectively managing the client’s condition. Monitoring blood pressure helps assess the medication's efficacy in achieving the desired therapeutic outcome.
D) Decrease in low-density lipoproteins: Although reducing low-density lipoprotein (LDL) levels can benefit cardiovascular health, enalapril is not primarily prescribed for this purpose. Its effects on lipid levels are minimal compared to its role in lowering blood pressure and protecting renal function, making a decrease in LDL levels an irrelevant indicator of its therapeutic effect.
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Correct Answer is D
Explanation
A. Low fat diet: While a low-fat diet can be beneficial for overall cardiovascular health, it is not the most critical intervention for a client with Buerger's Disease. The primary concern is addressing the underlying causes of the disease rather than just dietary modifications.
B. Blood glucose control: This is important for clients with diabetes but is not specific to Buerger's Disease. Effective management of blood glucose levels does not directly address the primary issues associated with this condition.
C. Blood pressure control: Managing blood pressure is important for overall cardiovascular health; however, it is not the most immediate concern for a client with Buerger's Disease compared to smoking cessation.
D. Smoking cessation: This is the most critical intervention. Buerger's Disease is strongly associated with tobacco use, and smoking cessation is essential to halt the progression of the disease and improve symptoms. Educating the client about the importance of quitting smoking can lead to significant improvements in their condition and overall vascular health.
Correct Answer is ["A","C","D"]
Explanation
A) Furosemide: This is a loop diuretic that can lead to dehydration and electrolyte imbalances, both of which can contribute to orthostatic hypotension. The medication's diuretic effect can cause a significant drop in blood volume, increasing the risk of low blood pressure upon standing.
B) Simvastatin: This medication is used to lower cholesterol levels and is not associated with orthostatic hypotension. It does not have a direct impact on blood pressure or volume.
C) Losartan: As an angiotensin II receptor blocker (ARB), losartan is used to treat hypertension. It can cause vasodilation and may lead to orthostatic hypotension, particularly in elderly clients or those who are volume-depleted.
D) Nifedipine: This calcium channel blocker is used to treat hypertension and can cause vasodilation. It may lead to orthostatic hypotension as well, especially during dose adjustments or if the client is dehydrated.
E) Clopidogrel: This antiplatelet medication is used to prevent blood clots and does not directly cause orthostatic hypotension. Its primary action is to inhibit platelet aggregation, not to affect blood pressure.