A nurse is caring for a client who has open-angle glaucoma and a new prescription for acetazolamide. Prior to administering the first dose, the nurse should ask the client if they have an allergy to which of the following medication classifications?
Nitrates
Sulfa-based medications
Mostly cloudy
Antilipemic agents
Proton pump inhibitors
The Correct Answer is B
Rationale:
A. Nitrates: Nitrates are primarily used to manage angina or heart conditions and are unrelated to acetazolamide or its potential for allergic reactions.
B. Sulfa-based medications: Acetazolamide is a carbonic anhydrase inhibitor that contains sulfonamide groups. Clients with a sulfa allergy may experience a cross-sensitivity reaction, so it's important to confirm any history of sulfa allergies before administration.
C. Mostly cloudy: This option does not relate to any medication classification and is incorrect.
D. Antilipemic agents: Antilipemics are used to lower cholesterol and are not related to acetazolamide or its potential for allergic reactions.
E. Proton pump inhibitors: Proton pump inhibitors are used to reduce stomach acid and do not have a known cross-sensitivity with acetazolamide.
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Correct Answer is A
Explanation
Rationale:
A. Frequent sputum tests may be needed to monitor the effectiveness of isoniazid, particularly in assessing the resolution of tuberculosis infection.
B. Isoniazid is usually prescribed for a minimum of six months for tuberculosis treatment, not just a month. Thus, stopping after one month is incorrect.
C. Antacids containing aluminum should not be taken concurrently with isoniazid, as they can interfere with the absorption of the medication, reducing its effectiveness.
D. Constipation is not a common side effect of isoniazid. The more frequent side effects include peripheral neuropathy and liver toxicity, making this statement incorrect.
Correct Answer is C
Explanation
Rationale:
A. Applying a warming blanket is not appropriate, as it may exacerbate the client's reaction to the infusion and is not a standard pre-medication strategy.
B. Infusing amphotericin B deoxycholate over 1 hour is too rapid; it is typically infused over 2-6 hours to minimize adverse effects.
C. Administering diphenhydramine prior to the administration of amphotericin B can help prevent or alleviate infusion-related reactions such as fever and chills, which the client experienced during previous infusions.
D. Monitoring vital signs once per hour following administration is insufficient; vital signs should be monitored more frequently during and immediately after the infusion to promptly detect and address any adverse reactions.