A nurse is caring for a client who has open-angle glaucoma and a new prescription for acetazolamide. Prior to administering the first dose, the nurse should ask the client if they have an allergy to which of the following medication classifications?
Nitrates
Sulfa-based medications
Mostly cloudy
Antilipemic agents
Proton pump inhibitors
The Correct Answer is B
Rationale:
A. Nitrates: Nitrates are primarily used to manage angina or heart conditions and are unrelated to acetazolamide or its potential for allergic reactions.
B. Sulfa-based medications: Acetazolamide is a carbonic anhydrase inhibitor that contains sulfonamide groups. Clients with a sulfa allergy may experience a cross-sensitivity reaction, so it's important to confirm any history of sulfa allergies before administration.
C. Mostly cloudy: This option does not relate to any medication classification and is incorrect.
D. Antilipemic agents: Antilipemics are used to lower cholesterol and are not related to acetazolamide or its potential for allergic reactions.
E. Proton pump inhibitors: Proton pump inhibitors are used to reduce stomach acid and do not have a known cross-sensitivity with acetazolamide.
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Correct Answer is B
Explanation
Rationale:
A. A decrease in the amount of gastric acid production: Alosetron is not used to decrease gastric acid production. This effect is more associated with medications such as proton pump inhibitors or H2 blockers.
B. A decrease in the frequency of defecation: Alosetron is used to treat irritable bowel syndrome with diarrhea (IBS-D) by reducing bowel movement frequency and improving stool consistency.
C. An increase in gastric motility: Alosetron works by decreasing intestinal motility, which helps reduce diarrhea, not by increasing it.
D. An increase in the absorption of water into the intestine: Alosetron does not specifically increase water absorption into the intestine. Its primary effect is slowing intestinal transit to reduce diarrhea.
Correct Answer is D
Explanation
Rationale:
A. Lactated Ringer's: This solution is isotonic and is typically used for fluid resuscitation, not for hypotonic treatment.
B. 0.9% sodium chloride: This is isotonic saline and does not qualify as a hypotonic solution.
C. 3% sodium chloride: This solution is hypertonic and used to treat severe hyponatremia, not hypotonic hydration.
D. 0.45% sodium chloride: This is the correct choice as it is a hypotonic solution that can help to hydrate cells by providing free water.