A nurse is caring for a client who has hyperlipidemia and a new prescription for colesevelam. The nurse should monitor the client for which of the following manifestations as an adverse effect of colesevelam?
Hyperglycemia.
Stomatitis.
Fever.
Constipation.
The Correct Answer is D
Choice A rationale
Hyperglycemia is not a common adverse effect of colesevelam. Colesevelam is primarily used to lower cholesterol levels and can also help control blood sugar levels in patients with type 2 diabetes.
Choice B rationale
Stomatitis, or inflammation of the mouth, is not typically associated with colesevelam. This medication works in the intestines and is not absorbed into the bloodstream, so it does not commonly cause systemic side effects.
Choice C rationale
Fever is not a known adverse effect of colesevelam. The medication’s side effects are generally limited to the gastrointestinal system.
Choice D rationale
Constipation is a common adverse effect of colesevelam. This medication binds to bile acids in the intestines, which can lead to gastrointestinal side effects such as constipation.
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Correct Answer is D
Explanation
Choice A rationale
Sitagliptin is a DPP-4 inhibitor used to manage blood sugar levels in type 2 diabetes but does not specifically slow the progression of nephropathy.
Choice B rationale
Glipizide is a sulfonylurea that helps control blood sugar levels but does not have a direct effect on slowing nephropathy progression.
Choice C rationale
Metoprolol is a beta-blocker used to manage hypertension but does not specifically target nephropathy progression.
Choice D rationale
Losartan is an angiotensin II receptor blocker (ARB) that helps manage hypertension and has been shown to slow the progression of nephropathy in patients with type 2 diabetes.
Correct Answer is B
Explanation
Choice A rationale
Weight gain is not a common side effect of pramlintide. Monitoring for hypoglycemia is more critical.
Choice B rationale
Pramlintide can cause hypoglycemia, especially within 3 hours after administration. Monitoring for hypoglycemia is essential.
Choice C rationale
Pramlintide should be injected into the abdomen or thigh, not the upper arm.
Choice D rationale
Pramlintide should be administered immediately before a meal, not 30 minutes prior.