A nurse is caring for a client who has been taking captopril for one year. Which of the following laboratory values should the nurse review? (Select all that apply.)
Potassium level.
WBC with differential.
BUN level.
Hemoglobin level.
Glucose level.
Correct Answer : A,B,C
Choice A rationale
Potassium level should be reviewed because captopril can cause hyperkalemia due to its effect on aldosterone secretion.
Choice B rationale
WBC with differential should be reviewed because captopril can cause neutropenia or agranulocytosis, especially in patients with renal impairment or collagen vascular disease.
Choice C rationale
BUN level should be reviewed because captopril can affect renal function, leading to increased BUN levels.
Choice D rationale
Hemoglobin level is not typically affected by captopril, so it is not a priority for review.
Choice E rationale
Glucose level is not typically affected by captopril, so it is not a priority for review.
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Correct Answer is D
Explanation
Choice A rationale
Sitagliptin is a DPP-4 inhibitor used to manage blood sugar levels in type 2 diabetes but does not specifically slow the progression of nephropathy.
Choice B rationale
Glipizide is a sulfonylurea that helps control blood sugar levels but does not have a direct effect on slowing nephropathy progression.
Choice C rationale
Metoprolol is a beta-blocker used to manage hypertension but does not specifically target nephropathy progression.
Choice D rationale
Losartan is an angiotensin II receptor blocker (ARB) that helps manage hypertension and has been shown to slow the progression of nephropathy in patients with type 2 diabetes.
Correct Answer is A
Explanation
Choice A rationale
Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose, including respiratory depression. It binds to opioid receptors and displaces the opioid molecules, reversing their effects.
Choice B rationale
Bisacodyl is a stimulant laxative used to treat constipation. It does not have any effect on opioid-induced respiratory depression.
Choice C rationale
Flumazenil is a benzodiazepine antagonist used to reverse the effects of benzodiazepines, not opioids. It is not effective in treating opioid-induced respiratory depression.
Choice D rationale
Pentazocine is an opioid agonist-antagonist used for pain relief. It does not reverse opioid-induced respiratory depression and can potentially worsen the condition.