A nurse is caring for a client who has active pulmonary tuberculosis (TB) and a new prescription for rifampin. The nurse should instruct the client that they should expect which of the following clinical manifestations while taking this medication?
Staining of teeth
Orange colored secretions
Constipation
White-colored stools
The Correct Answer is B
A. Staining of teeth: Rifampin is not known to stain teeth.
B. Orange colored secretions: Rifampin commonly causes orange discoloration of body fluids, including urine, tears, and sweat. This is harmless but can be alarming if the client is not forewarned.
C. Constipation: Constipation is not a typical side effect of rifampin.
D. White-colored stools: Rifampin does not cause white-colored stools, but bile duct obstruction could.
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Correct Answer is ["A","C"]
Explanation
A. Fluoroquinolones: Fluoroquinolones, such as ciprofloxacin and levofloxacin, are known to have the potential to prolong the QT interval, increasing the risk of arrhythmias like Torsades de Pointes.
B. Penicillins: Penicillins do not typically cause QT prolongation. Their adverse effects are more likely to include allergic reactions or gastrointestinal disturbances.
C. Macrolides: Macrolides, such as azithromycin and erythromycin, are associated with QT interval prolongation and an increased risk of cardiac arrhythmias.
D. Beta-Lactams: Beta-lactams, which include penicillins and cephalosporins, are not commonly associated with QT prolongation. They are more likely to cause allergic reactions.
E. Cephalosporins: Cephalosporins are not typically associated with QT prolongation. They share a similar beta-lactam structure to penicillins.
Correct Answer is B
Explanation
A. Medications will need to be taken until the Mantoux test is negative: The Mantoux test (PPD) is used for diagnosis, not for monitoring treatment efficacy.
B. A typical course of treatment usually involves 6 months of consistent medication use. TB treatment typically requires at least 6 months of consistent medication adherence to fully eradicate the bacteria and prevent resistance.
C. Medications will need to be taken for the rest of the client's life, even if the client feels better: This is inaccurate. TB treatment is time-limited, though the full course must be completed.
D. The client's family will also need to take medications to prevent infection: Prophylactic treatment is not usually required for all family members, though they may need screening.