A nurse is caring for a client who has a systemic fungal infection and is receiving IV amphotericin B deoxycholate. During previous infusions, the client developed a fever and chills. Which of the following actions should the nurse take?
Apply a warming blanket prior to administration.
Infuse the medication over 1 hr.
Administer diphenhydramine prior to administration.
Monitor vital signs once per hour following administration.
The Correct Answer is C
Rationale:
A. Applying a warming blanket is not appropriate, as it may exacerbate the client's reaction to the infusion and is not a standard pre-medication strategy.
B. Infusing amphotericin B deoxycholate over 1 hour is too rapid; it is typically infused over 2-6 hours to minimize adverse effects.
C. Administering diphenhydramine prior to the administration of amphotericin B can help prevent or alleviate infusion-related reactions such as fever and chills, which the client experienced during previous infusions.
D. Monitoring vital signs once per hour following administration is insufficient; vital signs should be monitored more frequently during and immediately after the infusion to promptly detect and address any adverse reactions.
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Correct Answer is B
Explanation
Rationale:
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B. Granisetron is an antiemetic medication used to prevent nausea and vomiting, which are common adverse effects of topotecan.
C. Insulin lispro is a rapid-acting insulin used to control blood sugar levels and does not relate to the adverse effects of topotecan.
D. Docusate sodium is a stool softener used to prevent constipation, but it does not specifically address the nausea and vomiting associated with chemotherapy.
E. Prednisone is a corticosteroid that may be used for other indications but is not primarily indicated for treating the nausea and vomiting caused by topotecan.
Correct Answer is D
Explanation
Rationale:
A. This statement is incorrect because omeprazole is not an antibiotic and does not kill bacteria; it is a proton pump inhibitor (PPI) that reduces acid production.
B. This statement is incorrect; omeprazole does not neutralize stomach acid, but rather decreases its production.
C. This statement is also incorrect; omeprazole does not coat the stomach lining; it works by inhibiting the proton pumps in the stomach lining to reduce acid secretion.
D. This statement is correct; omeprazole reduces stomach acid production, which is beneficial for managing GERD symptoms.