A nurse is caring for a 3-day-old newborn and suspects Hirschsprung disease. What finding best supports the nurse's concern?
The infant has passed several tar-like stools.
The infant has not gained weight and has stooled once.
The infant has not stooled.
The infant has passed hard, pellet-like stools.
The Correct Answer is C
Rationale:
A. Passing tar-like stools is normal for newborns within the first few days of life and does not indicate Hirschsprung disease.
B. Limited stooling and poor weight gain may suggest feeding issues but are not as indicative of Hirschsprung disease as the absence of stool.
C. The absence of stool (failure to pass meconium within 24-48 hours) is a classic sign of Hirschsprung disease, a condition where the absence of ganglion cells in the intestines leads to a blockage.
D. Passing hard, pellet-like stools may indicate constipation but is not specific to Hirschsprung disease, especially in a newborn.
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Correct Answer is B
Explanation
Rationale:
A. PKU is typically diagnosed through a blood test, not a urine test. The blood test measures phenylalanine levels, which are elevated in PKU.
B. Untreated PKU can lead to severe cognitive deficits and developmental delays due to the accumulation of phenylalanine, which is toxic to the brain. Early detection and treatment can prevent these outcomes.
C. In PKU, the urine does not typically contain high levels of phenyl pyruvic acid; it is the blood levels of phenylalanine that are elevated.
D. The effects of PKU are not reversible; however, with early and consistent treatment, such as a strict low-phenylalanine diet, the symptoms can be managed effectively.
Correct Answer is A
Explanation
Rationale:
A. Bradycardia, constipation, and hypotonia are common symptoms associated with congenital hypothyroidism due to the reduced metabolism that results from decreased thyroid hormone levels.
B. Elevated serum T3 and T4 would not be expected in congenital hypothyroidism; these levels are typically low.
C. Tachycardia, diarrhea, and tremors are more indicative of hyperthyroidism, not hypothyroidism.
D. In congenital hypothyroidism, the thyroid-stimulating hormone (TSH) is typically elevated as the body attempts to stimulate the thyroid gland to produce more hormones.