A nurse is assessing a client who is receiving gemfibrozil. The nurse should identify which of the following findings as an adverse effect of this medication?
Dependent edema.
Muscle tenderness.
Tremors.
Hyperkalemia.
The Correct Answer is B
Choice A rationale
Dependent edema is not a common adverse effect of gemfibrozil. It is more commonly associated with other conditions such as heart failure.
Choice B rationale
Muscle tenderness is a known adverse effect of gemfibrozil. It can indicate myopathy or rhabdomyolysis, which are serious conditions that require medical attention.
Choice C rationale
Tremors are not a common adverse effect of gemfibrozil. They are more commonly associated with neurological conditions or other medications.
Choice D rationale
Hyperkalemia is not a common adverse effect of gemfibrozil. It is more commonly associated with medications that affect renal function or potassium balance. .
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Correct Answer is D
Explanation
Choice A rationale
Sitagliptin is a DPP-4 inhibitor used to manage blood sugar levels in type 2 diabetes but does not specifically slow the progression of nephropathy.
Choice B rationale
Glipizide is a sulfonylurea that helps control blood sugar levels but does not have a direct effect on slowing nephropathy progression.
Choice C rationale
Metoprolol is a beta-blocker used to manage hypertension but does not specifically target nephropathy progression.
Choice D rationale
Losartan is an angiotensin II receptor blocker (ARB) that helps manage hypertension and has been shown to slow the progression of nephropathy in patients with type 2 diabetes.
Correct Answer is A
Explanation
Choice A rationale
Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose, including respiratory depression. It binds to opioid receptors and displaces the opioid molecules, reversing their effects.
Choice B rationale
Bisacodyl is a stimulant laxative used to treat constipation. It does not have any effect on opioid-induced respiratory depression.
Choice C rationale
Flumazenil is a benzodiazepine antagonist used to reverse the effects of benzodiazepines, not opioids. It is not effective in treating opioid-induced respiratory depression.
Choice D rationale
Pentazocine is an opioid agonist-antagonist used for pain relief. It does not reverse opioid-induced respiratory depression and can potentially worsen the condition.