A nurse is assessing a client who has been taking sertraline (Zoloft) for 2 weeks. The nurse should identify which of the following findings as an indication that the medication is effective?
The client's blood pressure is within the expected reference range.
The client reports a recent weight gain.
The client reports an increase in mood.
The client's legs are not swollen.
The Correct Answer is C
A. While maintaining blood pressure within the expected range is important, it does not specifically indicate the effectiveness of sertraline, which is an antidepressant.
B. Weight gain can occur with some antidepressants, but it is not a direct indicator of their effectiveness.
C. An increase in mood is a primary goal of treatment with sertraline, and reporting this improvement suggests that the medication is having a positive effect.
D. The absence of swollen legs is not a relevant indicator for assessing the effectiveness of sertraline, as it does not relate to mood or depression symptoms.
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Correct Answer is C
Explanation
A. While liver failure may affect excretion indirectly, it primarily impacts metabolism more significantly.
B. Absorption is typically not directly affected by liver function, though it can be influenced by other factors.
C. The liver is crucial for drug metabolism; chronic liver failure impairs the liver's ability to metabolize medications effectively, leading to potential toxicity.
D. Distribution may be altered due to changes in plasma proteins or blood flow, but the most significant impact occurs in metabolism.
Correct Answer is ["D","E","F"]
Explanation
A. Excessive sweating is not typically associated with anticholinergic medications like scopolamine; in fact, these medications can lead to decreased sweating.
B. Bradycardia can occur with certain medications but is more commonly associated with other drug classes rather than scopolamine, which typically causes tachycardia.
C. Diarrhea is not a common side effect of scopolamine; instead, anticholinergics often cause constipation.
D. Urinary retention is a known side effect of scopolamine due to its anticholinergic properties, which can affect bladder function.
E. Constipation is a common side effect of anticholinergic medications, including scopolamine.
F. Dry mouth is another common side effect due to decreased salivary secretions resulting from anticholinergic activity.