A nurse is administering drugs to a 70-year-old patient who has a reduced plasma albumin level. When assessing the patient for therapeutic outcomes of drug therapy, the nurse will also be careful to observe for
possible drug toxicity.
decreased therapeutic effects.
altered drug absorption.
increased drug metabolism.
The Correct Answer is A
A. A reduced plasma albumin level can lead to increased free drug levels in the bloodstream, raising the risk of drug toxicity, particularly for highly protein-bound medications.
B. Decreased therapeutic effects are less likely because the decrease in albumin can lead to higher free drug concentrations, which may actually increase effects rather than decrease them.
C. Altered drug absorption is generally not directly influenced by plasma albumin levels; it relates more to gastrointestinal factors.
D. Increased drug metabolism is not a direct consequence of lower albumin levels; instead, the concern is primarily about increased free drug concentrations and potential toxicity.
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Correct Answer is A
Explanation
A. Reye syndrome is correct because administering aspirin to children, especially during viral illnesses like the flu, can lead to this serious and potentially fatal condition characterized by acute encephalopathy and liver failure.
B. Excess antiplatelet action is incorrect; while aspirin does have antiplatelet effects, this is not the primary concern in a child with a viral illness.
C. Asthma is incorrect; while some individuals with asthma may have sensitivity to aspirin, it is not specifically related to the child's flulike illness.
D. Salicylate poisoning is incorrect; while high doses of aspirin can lead to toxicity, the immediate risk in the context of flu-like illness is Reye syndrome, which is a more specific concern.
Correct Answer is A
Explanation
A. Confirming that the medication prescribed is the drug of choice for the specific microorganism is crucial in ensuring effective treatment, as the right drug will target the identified infection.
B. Teaching the client that significant adverse effects are expected and must be endured is not a supportive approach; the focus should be on managing and minimizing adverse effects rather than accepting them.
C. Administering antihistamines may not be relevant for all patients undergoing anti-infective treatment and is not a primary strategy for ensuring treatment success.
D. Monitoring for signs of arrhythmias or cardiac ischemia is not directly related to ensuring the success of anti-infective treatment; it may be necessary for certain medications but does not address the effectiveness of anti-infectives specifically.