A nurse is administering drugs to a 70-year-old patient who has a reduced plasma albumin level. When assessing the patient for therapeutic outcomes of drug therapy, the nurse will also be careful to observe for
possible drug toxicity.
decreased therapeutic effects.
altered drug absorption.
increased drug metabolism.
The Correct Answer is A
A. A reduced plasma albumin level can lead to increased free drug levels in the bloodstream, raising the risk of drug toxicity, particularly for highly protein-bound medications.
B. Decreased therapeutic effects are less likely because the decrease in albumin can lead to higher free drug concentrations, which may actually increase effects rather than decrease them.
C. Altered drug absorption is generally not directly influenced by plasma albumin levels; it relates more to gastrointestinal factors.
D. Increased drug metabolism is not a direct consequence of lower albumin levels; instead, the concern is primarily about increased free drug concentrations and potential toxicity.
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Correct Answer is B
Explanation
A. This statement is accurate as antiviral drugs primarily reduce the severity and duration of viral infections but do not prevent transmission to others.
B. The statement that "antivirals are the cure for viral infections" is incorrect, as most antivirals manage symptoms or reduce viral load rather than completely curing the infection, indicating a need for further instruction.
C. This statement is correct; following prescribed application guidelines for topical antivirals is essential to avoid skin irritation or decreased efficacy.
D. This statement is also correct, as using gloves or a finger cot is recommended to prevent contamination and protect the healthcare worker from exposure while applying topical antivirals.
Correct Answer is D
Explanation
A. While historical context is useful, the development of antimicrobials primarily began in the early 20th century, notably with penicillin discovered by Alexander Fleming in 1928.
B. This statement is incorrect; fluoroquinolones primarily inhibit bacterial DNA synthesis rather than directly affecting the cell wall.
C. Selective toxicity is a principle of antimicrobial action but does not directly explain how a specific antimicrobial works therapeutically.
D. Penicillin specifically interferes with the synthesis of the bacterial cell wall, leading to cell lysis and death of the bacteria, which is a fundamental mechanism of action for this antibiotic.