A nurse is administering bumetanide to a client who has ascites. The nurse should recognize that which of the following findings is an expected therapeutic effect of this medication?
Decreased excretion of urine sodium.
Increased urinary output.
Decreased serum glucose.
Increased blood pressure.
The Correct Answer is B
Choice A rationale
Decreased excretion of urine sodium is not an expected therapeutic effect of bumetanide. Bumetanide is a loop diuretic that works by inhibiting the reabsorption of sodium and chloride in the ascending loop of Henle, leading to increased excretion of sodium and water.
Choice B rationale
Increased urinary output is the expected therapeutic effect of bumetanide. As a potent loop diuretic, bumetanide increases the excretion of water and electrolytes, which helps reduce fluid accumulation in conditions like ascites.
Choice C rationale
Decreased serum glucose is not associated with bumetanide. Bumetanide primarily affects fluid and electrolyte balance and does not have a significant impact on blood glucose levels.
Choice D rationale
Increased blood pressure is not an expected effect of bumetanide. On the contrary, bumetanide can help lower blood pressure by reducing fluid volume and decreasing the workload on the heart.
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Correct Answer is C
Explanation
Choice A rationale
Crushing hydroxychloroquine tablets can alter the drug’s release and absorption, potentially leading to suboptimal therapeutic effects or increased side effects.
Choice B rationale
Discontinuing hydroxychloroquine when symptoms subside can lead to a flare-up of rheumatoid arthritis symptoms. It is important to continue the medication as prescribed to maintain disease control.
Choice C rationale
Regular eye exams are necessary while taking hydroxychloroquine because the medication can cause retinal toxicity, which can lead to vision changes or loss if not monitored and managed appropriately.
Choice D rationale
Taking a double dose of hydroxychloroquine can increase the risk of side effects and toxicity. It is important to take the medication as prescribed and not to double up on doses.
Correct Answer is D
Explanation
Choice A rationale
Asthma is not a contraindication for sumatriptan. Sumatriptan is a selective serotonin receptor agonist used to treat migraines by constricting blood vessels in the brain. It does not have a significant impact on respiratory conditions like asthma.
Choice B rationale
Kidney disease is not a contraindication for sumatriptan. However, caution is advised when using sumatriptan in patients with severe renal impairment due to potential accumulation of the drug and its metabolites.
Choice C rationale
Rheumatoid arthritis is not a contraindication for sumatriptan. Sumatriptan’s mechanism of action does not interfere with the inflammatory processes involved in rheumatoid arthritis.
Choice D rationale
Coronary artery disease (CAD) is a contraindication for sumatriptan. Sumatriptan can cause vasoconstriction of coronary arteries, which can exacerbate CAD and increase the risk of myocardial infarction or other cardiac events.