A client newly prescribed niacin (Nicotinic Acid) presents to the healthcare setting with complaints of flushing following doses. Which of the following medications would the nurse anticipate being administered?
Beta Blockers
Calcium Channel Blockers
NSAIDs
Fibric Acid Derivatives
The Correct Answer is C
A. Beta blockers are used to manage blood pressure and heart rate but are not effective in reducing niacin-induced flushing.
B. Calcium channel blockers help to relax blood vessels but do not address the flushing side effect caused by niacin.
C. NSAIDs, like aspirin, can help reduce the flushing associated with niacin. This flushing occurs due to prostaglandin release, which NSAIDs can inhibit.
D. While fibric acid derivatives are used to lower cholesterol, they do not alleviate the flushing side effect of niacin.
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Correct Answer is C
Explanation
A. While hormonal contraceptives can affect blood pressure, the risk of significant hypertension is less immediate than thromboembolism.
B. Dysfunctional uterine bleeding can occur but is generally not as serious as thromboembolism and may resolve with continued use.
C. Combination birth control pills increase the risk of thromboembolic events, such as deep vein thrombosis (DVT) and pulmonary embolism, making it essential to monitor for signs of these complications.
D. Osteoporosis is a long-term concern but is not an acute effect of combination birth control pills; monitoring for thromboembolism is more critical.
Correct Answer is B
Explanation
A. Discontinuing metformin 24 hours before a CT scan is longer than necessary and not standard practice.
B. It is generally recommended that metformin be held for at least 12 hours before the administration of IV contrast to reduce the risk of lactic acidosis, especially in clients with renal impairment.
C. Six hours is insufficient time to ensure the medication is cleared from the system, considering the potential risks.
D. Discontinuing metformin for 48 hours is overly cautious and not necessary unless there are complications that arise after the contrast is administered.