A client has been taking propylthiouracil (PTU) for 8 weeks. Which statement by the client would indicate the drug is having its desired effects? (Select all that apply).
"My skin is not bruising as much."
“I am sleeping so much better."
"I don't feel as anxious as I once did."
“I can't seem to gain any weight no matter how much I eat."
"My menstruation is returning back to its regular cycle."
"My heart doesn't seem to be racing anymore."
Correct Answer : B,C,E,F
A. Bruising is typically related to anticoagulant effects or blood disorders and not directly tied to the desired effects of PTU.
B. Improved sleep is an indicator that hyperthyroidism symptoms, such as insomnia, are being managed effectively.
C. A decrease in anxiety can suggest effective management of hyperthyroidism, as anxiety is a common symptom of this condition.
D. Weight loss or inability to gain weight is usually a symptom of hyperthyroidism, so this statement would indicate that PTU is not achieving the desired effect.
E. A return to regular menstruation can indicate improved thyroid function, as hyperthyroidism can disrupt menstrual cycles.
F. Reduced heart rate and the absence of palpitations suggest effective management of hyperthyroidism symptoms, indicating the drug is having the desired effect.
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Correct Answer is C
Explanation
A. Risperidone is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder, not first-line treatment for depression.
B. Haloperidol is a typical antipsychotic used mainly for acute psychosis and agitation, not for treating depression.
C. Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that is widely recognized as a first-line treatment for depression due to its efficacy and relatively favorable side effect profile.
D. Clozapine is an atypical antipsychotic reserved for treatment-resistant schizophrenia and is not indicated for the treatment of depression.
Correct Answer is D
Explanation
A. Diabetes Mellitus is not a contraindication for promethazine, although caution may be needed regarding metabolic control.
B. Chronic Kidney Disease does not specifically contraindicate the use of promethazine, but dosage adjustments may be necessary due to altered drug metabolism.
C. Iron Deficiency Anemia does not contraindicate the use of promethazine and would not raise significant concerns for its administration.
D. Narrow-Angle Glaucoma is a contraindication for promethazine due to its anticholinergic properties, which can increase intraocular pressure and worsen glaucoma.