A client exhibits muscular tremors, drooling, gait changes, and spasms. When reviewing the client's medication history, which would the nurse most likely find?
antipsychotic agent
antidiabetic agent
general anesthetic
anticholinergic agent
The Correct Answer is A
A. An antipsychotic agent, particularly first-generation antipsychotics, can cause extrapyramidal symptoms such as tremors, drooling, gait changes, and spasms due to their dopamine-blocking effects in the brain.
B. An antidiabetic agent does not typically cause these neurological symptoms; its primary effects are related to glucose metabolism.
C. A general anesthetic is used to induce unconsciousness and does not generally result in muscular tremors or drooling.
D. An anticholinergic agent can cause side effects like dry mouth and constipation but does not typically lead to the muscular symptoms described; in fact, it may reduce drooling.
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Correct Answer is B
Explanation
A. Prothrombin time (PT) is used to monitor warfarin therapy, not heparin therapy.
B. Activated partial thromboplastin time (aPTT) is the primary laboratory test used to assess the effectiveness of heparin therapy, measuring the time it takes for blood to clot and ensuring therapeutic levels.
C. The International normalized ratio (INR) is also related to warfarin therapy rather than heparin.
D. Serum potassium level is not relevant for assessing heparin therapy but may be monitored for other reasons.
Correct Answer is B
Explanation
A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.
B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.
C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.
D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.