A client diagnosed with trichomoniasis is prescribed metronidazole. The nurse should instruct the client to avoid which contraindication associated with this medication?
Alcohol consumption
Tyramine based foods
Apple Juice
Soy beans
The Correct Answer is A
A. Alcohol consumption: Metronidazole has a disulfiram-like reaction with alcohol, which can cause severe nausea, vomiting, flushing, and tachycardia. Clients should avoid alcohol during and for at least 48 hours after the completion of metronidazole therapy.
B. Tyramine-based foods: Avoiding tyramine-rich foods is important with certain MAOIs due to the risk of hypertensive crisis, not with metronidazole.
C. Apple Juice: There is no significant interaction between metronidazole and apple juice.
D. Soy beans: Soybeans do not have an interaction with metronidazole.
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Correct Answer is D
Explanation
A. Macrolides: Macrolides, such as azithromycin or erythromycin, are often used as alternatives in clients with a penicillin allergy, as they do not have a beta-lactam ring and generally do not cause cross-reactivity.
B. Antiretrovirals: Antiretrovirals are used for treating HIV/AIDS and are unrelated to penicillin antibiotics, with no cross-sensitivity concerns.
C. Antimalarials: Antimalarial drugs are used to treat malaria and are not related to penicillin antibiotics, so they would not be a concern for cross-sensitivity.
D. Cephalosporins: Cephalosporins have a beta-lactam structure similar to penicillins, which can sometimes cause cross-reactivity in clients with a penicillin allergy. However, the risk is lower with newer generations.
Correct Answer is B
Explanation
A. Uterine cancer: No known contraindications exist between this condition and sulfamethoxazole/trimethoprim.
B. Client taking captopril for hypertension: Sulfamethoxazole/trimethoprim can increase potassium levels, and captopril (an ACE inhibitor) also raises potassium levels. Using these drugs together increases the risk of hyperkalemia, a dangerous condition.
C. Osteoporosis: This condition does not contraindicate the use of sulfamethoxazole/trimethoprim.
D. Multiple Sclerosis: No known contraindications exist for this condition with sulfamethoxazole/trimethoprim.