A client diagnosed with trichomoniasis is prescribed metronidazole. The nurse should instruct the client to avoid which contraindication associated with this medication?
Alcohol consumption
Tyramine based foods
Apple Juice
Soy beans
The Correct Answer is A
A. Alcohol consumption: Metronidazole has a disulfiram-like reaction with alcohol, which can cause severe nausea, vomiting, flushing, and tachycardia. Clients should avoid alcohol during and for at least 48 hours after the completion of metronidazole therapy.
B. Tyramine-based foods: Avoiding tyramine-rich foods is important with certain MAOIs due to the risk of hypertensive crisis, not with metronidazole.
C. Apple Juice: There is no significant interaction between metronidazole and apple juice.
D. Soy beans: Soybeans do not have an interaction with metronidazole.
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Correct Answer is A
Explanation
A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.
B. Uterine Cancer: Zidovudine is not associated with uterine cancer.
C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.
D. Thromboembolic Events: This is not a known black box warning for zidovudine.
Correct Answer is B
Explanation
A. Thromboembolic events: This is not a black box warning for ciprofloxacin.
B. This drug has a black box warning for causing tendon rupture: Ciprofloxacin, a fluoroquinolone, has a black box warning for the risk of tendonitis and tendon rupture, especially in older adults or those on corticosteroids.
C. Endometrial cancers: Ciprofloxacin is not associated with cancer.
D. Breast cancer: There is no link between ciprofloxacin and breast cancer.