A client diagnosed with strep throat requires antibiotics for treatment. With an allergy to penicillin, the nurse understands which medication should be avoided due to cross-sensitivity with penicillin medications?
Macrolides
Antiretrovirals
Antimalarials
Cephalosporins
The Correct Answer is D
A. Macrolides: Macrolides, such as azithromycin or erythromycin, are often used as alternatives in clients with a penicillin allergy, as they do not have a beta-lactam ring and generally do not cause cross-reactivity.
B. Antiretrovirals: Antiretrovirals are used for treating HIV/AIDS and are unrelated to penicillin antibiotics, with no cross-sensitivity concerns.
C. Antimalarials: Antimalarial drugs are used to treat malaria and are not related to penicillin antibiotics, so they would not be a concern for cross-sensitivity.
D. Cephalosporins: Cephalosporins have a beta-lactam structure similar to penicillins, which can sometimes cause cross-reactivity in clients with a penicillin allergy. However, the risk is lower with newer generations.
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Correct Answer is C
Explanation
A. Amoxicillin/clavulanate (Augmentin): Amoxicillin/clavulanate is a broad-spectrum antibiotic but not the preferred choice for anthrax exposure.
B. Nystatin (Mycostatin): Nystatin is an antifungal medication used for treating fungal infections, such as oral thrush or cutaneous candidiasis. It is not effective against anthrax, which is a bacterial infection.
C. Ciprofloxacin (Cipro): Ciprofloxacin, a fluoroquinolone, is the recommended first-line antibiotic for treating anthrax exposure due to its efficacy against Bacillus anthracis, the bacteria causing anthrax.
D. Tamoxifen: Tamoxifen is a selective estrogen receptor modulator (SERM) used primarily in the treatment of breast cancer. It has no role in treating bacterial infections like anthrax.
Correct Answer is A
Explanation
A. Alcohol consumption: Metronidazole has a disulfiram-like reaction with alcohol, which can cause severe nausea, vomiting, flushing, and tachycardia. Clients should avoid alcohol during and for at least 48 hours after the completion of metronidazole therapy.
B. Tyramine-based foods: Avoiding tyramine-rich foods is important with certain MAOIs due to the risk of hypertensive crisis, not with metronidazole.
C. Apple Juice: There is no significant interaction between metronidazole and apple juice.
D. Soy beans: Soybeans do not have an interaction with metronidazole.