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A client diagnosed with hyperlipidemia has been taking atorvastatin for several months. How can the therapeutic effect of the medication be determined?

A.

assessing the client's resting heart rate and postural blood pressures

B.

reviewing the client's laboratory blood work results

C.

assessing the client's exercise tolerance and activities of daily living

D.

performing a focused cardiac assessment

Answer and Explanation

The Correct Answer is B

A. While resting heart rate and blood pressure are important for overall cardiovascular health, they do not specifically assess the effectiveness of atorvastatin in lowering lipid levels.  

 

B. Reviewing laboratory blood work results, particularly lipid panels, is essential to determine the therapeutic effect of atorvastatin, as it directly measures changes in cholesterol levels (such as LDL and total cholesterol).  

 

C. Assessing exercise tolerance and activities of daily living can provide insight into overall health and well-being but does not specifically evaluate the impact of atorvastatin on lipid levels.  

 

D. A focused cardiac assessment is beneficial for understanding cardiovascular health but is not specific for measuring the effectiveness of lipid-lowering therapy with atorvastatin.


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Correct Answer is B

Explanation

A. Decreased appetite may occur but is not the most critical concern in this context.

B. The combination of metoclopramide, which can influence serotonin pathways, with certain antidepressants, especially SSRIs, increases the risk of serotonin syndrome, a potentially life-threatening condition.

C. While some antidepressants can influence blood pressure, monitoring for elevated blood pressure is not the primary concern with metoclopramide.

D. There is no evidence to suggest that metoclopramide enhances the effects of antidepressants; the focus should be on potential adverse interactions instead.

Correct Answer is D

Explanation

A. While MAOIs may have some regulatory considerations, they are not classified under a scheduled drug classification like controlled substances.

B. MAOIs are effective in treating depression and anxiety disorders, which is not the reason for their limited use.

C. Although MAOIs can have some side effects, they are more notably associated with dietary and drug interactions rather than causing GI bleeding or esophageal varices.

D. MAOIs can cause dangerous interactions with foods that contain tyramine (like aged cheeses and fermented products) and certain medications, leading to hypertensive crises, making their use cautious and limiting in clinical practice.

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