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A client diagnosed with a urinary tract infection (UTI) is prescribed sulfamethoxazole/trimethoprim. Which of the following conditions below would be a contraindication for this medication?

A.

Uterine cancer

B.

Client taking captopril for hypertension

C.

Osteoporosis

D.

Multiple Sclerosis

Answer and Explanation

The Correct Answer is B

A. Uterine cancer: No known contraindications exist between this condition and sulfamethoxazole/trimethoprim.

 

B. Client taking captopril for hypertension: Sulfamethoxazole/trimethoprim can increase potassium levels, and captopril (an ACE inhibitor) also raises potassium levels. Using these drugs together increases the risk of hyperkalemia, a dangerous condition.

 

C. Osteoporosis: This condition does not contraindicate the use of sulfamethoxazole/trimethoprim.

 

D. Multiple Sclerosis: No known contraindications exist for this condition with sulfamethoxazole/trimethoprim.


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View Related questions

Correct Answer is ["A","C"]

Explanation

A. Fluoroquinolones: Fluoroquinolones, such as ciprofloxacin and levofloxacin, are known to have the potential to prolong the QT interval, increasing the risk of arrhythmias like Torsades de Pointes.

B. Penicillins: Penicillins do not typically cause QT prolongation. Their adverse effects are more likely to include allergic reactions or gastrointestinal disturbances.

C. Macrolides: Macrolides, such as azithromycin and erythromycin, are associated with QT interval prolongation and an increased risk of cardiac arrhythmias.

D. Beta-Lactams: Beta-lactams, which include penicillins and cephalosporins, are not commonly associated with QT prolongation. They are more likely to cause allergic reactions.

E. Cephalosporins: Cephalosporins are not typically associated with QT prolongation. They share a similar beta-lactam structure to penicillins.

Correct Answer is A

Explanation

A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.

B. Uterine Cancer: Zidovudine is not associated with uterine cancer.

C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.

D. Thromboembolic Events: This is not a known black box warning for zidovudine.

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