A client diagnosed with a urinary tract infection (UTI) is prescribed sulfamethoxazole/trimethoprim. Which of the following conditions below would be a contraindication for this medication?
Uterine cancer
Client taking captopril for hypertension
Osteoporosis
Multiple Sclerosis
The Correct Answer is B
A. Uterine cancer: No known contraindications exist between this condition and sulfamethoxazole/trimethoprim.
B. Client taking captopril for hypertension: Sulfamethoxazole/trimethoprim can increase potassium levels, and captopril (an ACE inhibitor) also raises potassium levels. Using these drugs together increases the risk of hyperkalemia, a dangerous condition.
C. Osteoporosis: This condition does not contraindicate the use of sulfamethoxazole/trimethoprim.
D. Multiple Sclerosis: No known contraindications exist for this condition with sulfamethoxazole/trimethoprim.
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Correct Answer is D
Explanation
A. Tendon rupture: Tendon rupture is not a side effect associated with estrogen blockers.
B. Phlebitis: While thromboembolic events are a risk, phlebitis (inflammation of a vein) is not a typical concern.
C. Increased risk of lymphomas: Estrogen blockers are not known to increase the risk of lymphomas.
D. Thromboembolic events: Estrogen blockers, such as tamoxifen, are associated with an increased risk of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism).
Correct Answer is A
Explanation
A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.
B. Uterine Cancer: Zidovudine is not associated with uterine cancer.
C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.
D. Thromboembolic Events: This is not a known black box warning for zidovudine.