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A client arrives at the healthcare setting currently taking atorvastatin (Lipitor) daily. Which assessment finding associated with atorvastatin (Lipitor) would need immediate reporting to the healthcare provider?

A.

bradycardia

B.

dark-red urine

C.

elevated HDL cholesterol

D.

migraine headache

Answer and Explanation

The Correct Answer is B

A. Bradycardia is not a common side effect of atorvastatin and would not necessarily require immediate reporting unless it is significantly low and symptomatic.  

 

B. Dark-red urine could indicate the presence of myoglobinuria, which can occur due to rhabdomyolysis, a serious side effect of statins like atorvastatin that necessitates immediate medical attention.  

 

C. Elevated HDL cholesterol is generally a positive finding and does not require reporting unless it is part of a larger adverse effect context.  

 

D. A migraine headache, while concerning, is not a known side effect specifically associated with atorvastatin and may not require immediate intervention unless severe or persistent.


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View Related questions

Correct Answer is B

Explanation

A. Carvedilol is a beta-blocker that is often used in hypertension management but is not considered a first-line treatment.

B. Lisinopril, an ACE inhibitor, is a first-line treatment for hypertension due to its effectiveness and safety profile, making it a common choice for initial therapy.

C. Doxazosin is an alpha-1 blocker that can be used for hypertension but is not typically a first-line treatment due to the risk of side effects like hypotension.

D. Clonidine is a central alpha agonist used in certain situations for hypertension but is not considered a first-line therapy due to potential adverse effects and sedation.

Correct Answer is B

Explanation

A. A high first-pass effect means that a significant amount of the drug is metabolized by the liver before reaching systemic circulation, making oral administration less effective.

B. Morphine with a high first-pass effect will be more effective when administered via non-enteral routes, such as IV or subcutaneous, to bypass the liver's initial metabolism.

C. The first-pass effect does not influence the kidney’s rate of excretion but rather the liver’s initial metabolism of the drug.

D. The liver, not the kidneys, is responsible for the first-pass metabolism, which occurs before the drug reaches systemic circulation when taken orally.

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