A 45-year-old male patient present to the emergency department with a severe head injury following a car accident. His Glasgow Coma Scale (GCS) score is 8, and he shows signs of increased intracranial pressure (ICP). Which of the following interventions should be prioritized to manage his ICP?
Administering mannitol intravenously
Encouraging the patient to hyperventilate
Administering a high-dose corticosteroid
Performing a lumbar puncture immediately
The Correct Answer is A
A. Administering mannitol intravenously: Mannitol is an osmotic diuretic that helps reduce ICP by drawing fluid out of brain tissue and decreasing cerebral edema, making it a priority intervention.
B. Encouraging the patient to hyperventilate: Controlled hyperventilation may reduce ICP temporarily by lowering CO₂ levels and causing cerebral vasoconstriction. However, it should only be done cautiously under close monitoring, and other ICP management techniques like mannitol administration take priority.
C. Administering a high-dose corticosteroid: Corticosteroids are generally ineffective for reducing ICP in traumatic brain injury and are typically not recommended in this scenario.
D. Performing a lumbar puncture immediately: Lumbar puncture is contraindicated in cases of increased ICP because it may lead to brain herniation due to the sudden release of pressure.
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Correct Answer is B
Explanation
A. Interferon Gamma Release Assays (IGRAs): IGRAs are useful for detecting TB infection but do not confirm active TB disease. They measure the immune response to TB bacteria but don’t differentiate between latent and active infection.
B. Sputum culture: Sputum culture is the gold standard for confirming active TB because it identifies Mycobacterium tuberculosis bacteria directly, confirming active infection.
C. Tuberculin Skin Test (TST): The TST can indicate TB infection but cannot distinguish between latent and active TB, making it unsuitable as a confirmatory test for active disease.
D. Chest X-ray: A chest X-ray can show signs suggestive of TB but cannot confirm the presence of TB bacteria, so it is not definitive for diagnosing active TB.
Correct Answer is D
Explanation
A. Pulmonary Function Test (PFT). PFTs assess lung function but do not provide diagnostic information for infections like pneumonia.
B. Electrocardiogram (ECG). An ECG assesses heart function and would not help in diagnosing a respiratory infection like pneumonia.
C. Complete Blood Count (CBC). A CBC may indicate infection through elevated white blood cells, but it does not confirm pneumonia or identify its location in the lungs.
D. Chest X-ray. A chest X-ray is the most useful diagnostic tool to confirm pneumonia. It can reveal infiltrates or consolidation in the lungs, which are characteristic of pneumonia.