A 40-year old patient presents with symptoms suggestive of tuberculosis (TB). What is the confirmatory test for TB?
Interferon Gamma Release Assays (IGRAS)
Sputum culture
Tuberculin Skin Test (TST)
Chest X-ray
The Correct Answer is B
A. Interferon Gamma Release Assays (IGRAs): IGRAs are useful for detecting TB infection but do not confirm active TB disease. They measure the immune response to TB bacteria but don’t differentiate between latent and active infection.
B. Sputum culture: Sputum culture is the gold standard for confirming active TB because it identifies Mycobacterium tuberculosis bacteria directly, confirming active infection.
C. Tuberculin Skin Test (TST): The TST can indicate TB infection but cannot distinguish between latent and active TB, making it unsuitable as a confirmatory test for active disease.
D. Chest X-ray: A chest X-ray can show signs suggestive of TB but cannot confirm the presence of TB bacteria, so it is not definitive for diagnosing active TB.
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Correct Answer is D
Explanation
A. Mild wheezing: Mild wheezing can be a common symptom in COPD and does not immediately indicate a severe complication unless it worsens suddenly.
B. Fatigue and general malaise: Fatigue and malaise are often chronic in COPD and do not necessarily indicate an acute complication.
C. Increased sputum production: While increased sputum could suggest an infection, it is not the most urgent sign of a severe complication.
D. Sudden onset chest pain and dyspnea: Sudden chest pain and dyspnea are concerning for a pneumothorax or pulmonary embolism, both of which are potential complications in COPD and require immediate attention.
Correct Answer is C
Explanation
A. Influenza: Influenza typically presents with a high fever, muscle aches, and fatigue, which are not present in this case.
B. Strep Throat: Strep throat usually presents with a sore throat, high fever, and swollen lymph nodes, not nasal congestion or watery eyes.
C. Rhinitis: Rhinitis, particularly allergic rhinitis, causes symptoms such as sneezing, nasal congestion, watery eyes, and malaise without fever, making it the most likely diagnosis.
D. Bacterial Pharyngitis: Bacterial pharyngitis often presents with a sore throat, fever, and swollen lymph nodes, but typically does not include nasal congestion or watery eyes.