The nurse provides a client with a dose of the beta-selective adrenergic agonist isoproterenol. Which assessment finding indicates the medication is effective?
Constricted pupils
Warm, dry skin
Increased heart rate
Decreased urine output
The Correct Answer is C
A. Constricted pupils are not an expected response to isoproterenol, which generally causes dilation of the pupils due to sympathetic stimulation.
B. Warm, dry skin is not a direct indicator of the effectiveness of isoproterenol; it could result from various factors unrelated to the medication's action.
C. Increased heart rate indicates that isoproterenol, which is a beta-agonist, is effectively stimulating the beta-adrenergic receptors, leading to increased cardiac output and heart rate.
D. Decreased urine output is not a sign of effectiveness and could indicate adverse effects such as reduced renal perfusion.
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Correct Answer is B
Explanation
A. Excessive thirst is not a common adverse effect associated with albuterol.
B. Albuterol, a beta-agonist, can cause tachycardia as an adverse effect; a heart rate of 99 beats/min may indicate this response.
C. An oral temperature of 100°F may suggest a mild infection or other issues, but it is not a specific adverse effect of albuterol.
D. Diarrhea is not typically associated with albuterol use and is less likely to be attributed to the medication.
Correct Answer is D
Explanation
A. While historical context is useful, the development of antimicrobials primarily began in the early 20th century, notably with penicillin discovered by Alexander Fleming in 1928.
B. This statement is incorrect; fluoroquinolones primarily inhibit bacterial DNA synthesis rather than directly affecting the cell wall.
C. Selective toxicity is a principle of antimicrobial action but does not directly explain how a specific antimicrobial works therapeutically.
D. Penicillin specifically interferes with the synthesis of the bacterial cell wall, leading to cell lysis and death of the bacteria, which is a fundamental mechanism of action for this antibiotic.